国际生物医学工程杂志2014年10月第37卷第5期Int J Bi om edEng, O ctober2014,V01.37,N o.5· 论著·E酽一Cre诱导的Rosa26R.YFP报告基因系统标记小鼠造血干祖细胞的条件和效率检测罗琦尹洁孟歆怿杨冰雷蕾孙琰李丹丹王瑾王玺何景华【摘要】目的探索ERBcre诱导的黄色荧光蛋白( YFP) 报告基因系统标记小鼠造血干...
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The GluCre-ROSA26EYFP mouse: a new model for easy identification of living pancreatic α-cells. FEBS Lett., 581(22): 4235-40.Quoix N, Cheng-Xue R, Guiot Y, Herrera PL, Henquin J-C, Gilon P. The GluCre-ROSA26EYFP mouse: a new model for easy identification of living pancreatic ...
Hence, crossing ROSA26-EYFP mice with glucagon-Cre mice yielded a new strain of mice with EYFP expression restricted to α-cells. Comparison with two strains of control mice showed that the fluorescent α-cells of the GYY mouse model displayed normal characteristics and can thus reliably be ...
isletinsulinstreptozotocinhydrocortisonetransdifferentiationThe present study examines differences in metabolic and pancreatic islet adaptative responses following streptozotocin (STZ) and hydrocortisone (HC) administration in male and female transgenic GluCreERT2/Rosa26-eYFP mice. Mice received five daily doses...
Characterization of Cre activity in PLP/CreERT+; Rosa26-EYFPflox/+ mice.doi:10.1371/journal.pone.0089377.g001L. ZhiyongFang JieD. JenniferZhang LingliZuo Jian
We then generated two reporter lines of mice by inserting EYFP or ECFP cDNAs into the ROSA26 locus, preceded by a loxP-flanked stop sequence. These strains were tested by crossing them with transgenic strains expressing Cre in a ubiquitous (尾-actin-Cre) or a cell-specific (Isl1-Cre and ...
We then generated two reporter lines of mice by inserting EYFP or ECFP cDNAs into the ROSA26 locus, preceded by a loxP-flanked stop sequence. These strains were tested by crossing them with transgenic strains expressing Cre in a ubiquitous (尾-actin-Cre) or a cell-specific (Isl1-Cre and ...