A large number of studies have revealed that high expression of Nectin4 is closely related to tumor occurrence and development in various cancer types, but the manner in which Nectin4 protein contributes to the onset and development of these malignancies is yet unknown. The present review ...
Nectin-4 has recently been shown as a metastasis-associated protein in several cancers. In the following study, we have evaluated the expression of Nectin-4 inthe luminal B HER2 negative subtype breast cancer. The study group consisted of 147 patients presenting with primary unilateral breast ...
Nectin-4 has recently been shown as a metastasis-associated protein in several cancers. In the following study, we have evaluated the expression of Nectin-4 inthe luminal B HER2 negative subtype breast cancer. The study group consisted of 147 patients presenting with primary unilateral breast ...
Protein levels of nectin 4 were elevated in ovarian cancer cell lines and tissue compared with normal ovarian cell lines as demonstrated by Western immunoblotting, flow cytometry, and immunohistochemical staining of tissue microarray slides. Cleaved nectin 4 was detectable in a number of patient serum...
Nectin-4-dependent measles virus spread to the cynomolgus monkey tracheal epithelium: role of infected immune cells infiltrating the lamina propria. Nectin-4-dependent measles virus spread to the cynomolgus monkey tracheal epithelium: role of infected immune cells infiltrating the lamina propria. J ...
Role of the focal adhesion protein kindlin-1 in breast cancer growth and lung metastasis. J Natl Cancer Inst. 2011;103:1323–37. CAS PubMed Google Scholar Glukhova MA, Streuli CH. How integrins control breast biology. Curr Opin Cell Biol. 2013;25:633–41. CAS PubMed PubMed Central ...
2. Structure and function of ADAMs 3. ADAMs in breast cancer 4. Conclusion Conflict of interest statement Data availability statement CRediT authorship contribution statement Declaration of competing interest Acknowledgment ReferencesShow full outline Cited by (1) Figures (1) Tables (1) Table 1Vol...
microRNA in chemotherapy resistance Haoran LI1, 2, Burton B YANG1, 2, * 1Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto; 2Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada Chemotherapy has been widely used in treating cancer patients...
Colorectal cancer is a leading cause of cancer-related mortality worldwide, with Fluorouracil (5-FU)-based chemotherapy as the major treatment for advanced disease. Many patients with advanced colorectal cancer eventually succumb to the disease despite s
Furthermore, cell death depends on amounts of various members of Bcl2 family. For more information, read the text. Full size image The main adhesion molecules required for bone cell development and apoptosis are integrins, especially αvβ3 (vibronectin receptor integrin) and α2β1 (collagen...