The gut microbiome is considered as an organ that contributes to the regulation of host metabolism. Mammals possess an ‘extended genome’ of millions of microbial genomes located in the intestine: the microbiome. To date, there is rapidly booming eviden
The dominant benthic primary producers in coral reef ecosystems are complex holobionts with diverse microbiomes and metabolomes. In this study, we characterize the tissue metabolomes and microbiomes of corals, macroalgae, and crustose coralline algae via
The microbiota (bacteria, archaea, viruses, fungi, protozoa) inhabiting the human body are estimated to be in the range of 10–100 trillion [4]. The combined genetic material harbored by these microorganisms, known as the microbiome, far exceeds that of the human genome [5]. While the majo...
The Hessian fly is an obligate parasite of wheat causing significant economic damage, and triggers either a resistant or susceptible reaction. However, the molecular mechanisms of susceptibility leading to the establishment of the larvae are unknown. Lar
Mycotoxins are fungal metabolites that can cause various diseases in humans and animals. The adverse health effects of mycotoxins such as liver failure, immune deficiency, and cancer are well-described. However, growing evidence suggests an additional li
exenatide-4-treated patients had a mean improvement at 12 months on the Movement Disorders Society Unified Parkinson's Disease Rating Scale (MDS-UPDRS) of 2.7 points, compared with mean decline of 2.2 points in control patients [223] and that these motor and cognitive advantages persisted 12 mon...
Viral infections are the most critical among infectious diseases, especially those that can lead to chronic diseases. The control and the prevention of chronic diseases represent a challenge for public health organizations. These chronic diseases are the
Compost habitats sustain a vast ensemble of microbes specializing in the degradation of lignocellulosic plant materials and are thus important both for their roles in the global carbon cycle and as potential sources of biochemical catalysts for advanced
we assessed both their individual and combined effect on a hippocampus and age-dependent cognitive task in a cohort of 1638 twins (Fig.1b). Polymorphisms in the selected candidate genes, physical activity and three dietary measures: adherence to Mediterranean diet (MDS), healthy eating (HEI) and...
RNA splicing is an essential post-transcriptional mechanism that facilitates the excision of introns and the connection of exons to produce mature mRNA, which is essential for gene expression and proteomic diversity. In the liver, precise splicing regula