The main external factors that can affect the composition of the microbial community in generally healthy adults include major dietary changes and antibiotic therapy. Changes in some selected bacterial groups have been observed due to controlled changes to the normal diet e.g. high-protein diet, ...
addition, the current and emerging microbial interventions for cancer therapy as well as their clinical applications are summarized. Although many challenges remain for now, the great importance and full potential of the gut microbiota cannot be overstated for the development of individualized anti-cancer...
The essential properties of the gut microbiota, such as its stability, resilience, and diversity, need to be discussed, given its importance in human health [8]. The gut microbial community can be stable for years in healthy adults; thus, the microbiota has high stability. Homeostasis of the ...
The exact mechanism underlying brain injury in preterm infants is unclear. Intestinal flora plays a vital role in brain development and the maturation of the immune system in infants; however, detailed understanding of the gut microbiota-metabolite-brain axis in preterm infants is lacking. In this ...
IBS is generally characterized by abdominal pain, discomfort, and altered bowel habits. Although the etiology is multifactorial, recent understanding of the pathophysiology of IBS has revealed that variations in the normal gut microbiota may have a role to play in the low-grade intestinal inflammation...
Gut microbiome manipulation therefore represents an attractive proposition for aquaculture and has been suggested as a possible alternative to the use of broad-spectrum antibiotics in the management of disease, which is a major limitation of growth in this sector. Microbiota supplementation has also ...
The gut microbiome and disease The community of trillions of bacteria in the GI tract provides support to all aspects of the digestive system, such as breaking down nutrients, producing short-chain fatty acids, making vitamins and providing energy to the host and the other gut bacteria. ...
In situations where tissues experience persistent stimulation with inflammatory factors, the normal wound healing response becomes disrupted and the gradual accumulation of extracellular matrix ensues, culminating in the formation of scars or fibrosis. The progression of this pathological condition is a ...
The manipulation of intestinal microbes in animals has revealed connections between gut microbiota and both normal and pathological brain functions. The hope fueling this research is that gut microbiota could be harnessed to prevent and treat mental disorders. The links observed between an imbalance of...
Disruption of the normal, homeostatic composition and function of a microbiota within its ecological niche. Faecal microbiota transplantation (FMT). The transfer of faecal material from a donor to a recipient by lower or upper gastrointestinal tract endoscopy, enema or consumption of capsules of freeze...