Studies using antibodies raised against DNA helicase II of E.coli and applied to subcellular E.coli DNA replicating systems suggest that DNA helicase II participates in the unwinding of DNA molecules, which initiate replication as closed circles. A similar role for the rep protein has been ...
Replication refers to the cellular process of duplicating DNA molecules. During replication, each strand of the double-stranded DNA (dsDNA) serves as...Become a member and unlock all Study Answers Start today. Try it now Create an account Ask a question Our experts can answer your tough ...
The replicative helicase unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases. In eukaryotes, the replicative helicase is composed of the Cdc45 protein, the heterohexameric ring-shaped Mcm2-7 complex, and the tetrameric ...
The MCM complex controls the once per cell cycle DNA replication in eukaryotic cells. In a process known as DNA replication licensing, it primes chromatin for DNA replication by binding origins of DNA replication during the late M to early G1 phase of the cell cycle. Activated by S phase ...
Proton transfer across hydrogen bonds in DNA can produce non-canonical nucleobase dimers and is a possible source of single-point mutations when these forms mismatch under replication. Previous computational studies have revealed this process to be energ
DNA Replication:DNA replication is the process of formation of a new DNA strand from the parent strand by the use of certain enzymes such as polymerases, ligases, and topoisomerases. DNA replication takes place in the nucleus of the cell....
By both genetic and biochemical criteria, bacteriophage T4 catalyzes replication repair with two alternative sets of proteins, one including the gp32 SSB and the gp41 DNA helicase and the other including the UvsX recombinase. In each pathway, synthesis is conducted by the gp43 DNA polymerase. ...
Genomes are subject to a number of exogenous or endogenous DNA-damaging agents that cause DNA double-strand breaks (DSBs). These critical DNA lesions can r
A role of Werner helicase interacting protein 1 in the Fanconi Anemia DNA repair pathway T, Sommers JA, et al.: Werner Syndrome Helicase has a Critical Role in DNA Damage responses in the absence of a Functional Fanconi Anemia Pathway. Can... A Socha 被引量: 0发表: 2017年 Emergence of...
What is the purpose of DNA replication? What is helicase? Describe its role in DNA replication. What is the function of the sliding clamp in DNA replication? What is the role of DNA polymerase epsilon? What does the Cas9 enzyme do to DNA when it binds to the DNA? Explain. ...