Clinical Biochemistry of Inflammation and the Role of Connective Tissuedoi:10.1515/9783110861051-060Jacques Paul Borel
Chronic inflammation can also result from stimuli that initiate a low-grade and asymptomatic response.6 Although an inflammatory reaction can occur in any tissue exposed to an injurious stimulus, the hallmark of this process is the response of vascularized connective tissue.6 The first changes ...
To discuss the relationship between adipokines and connective tissue diseases, by putting special emphasis on the potential role of leptin, adiponectin, resistin, and other adipose tissue products in the pathogenesis of rheumatoid arthritis and systemic lupus erythematosus and on possible application of ad...
publicly-available proteomic datasets highlighted a potential role of the innate immune system and inflammation in myopia development, detailing specific signaling pathways involved such as Granzyme A (GzmA) and S100 family signaling in the retina, and activation of myofibroblast trans-differentiation in t...
While they are often regarded as inert, they actually exhibit considerable dynamic behavior in response to mechanical loads by modifying their extracellular matrix1. Tendons are dense connective tissues that contain longitudinal arrays of tenocytes. Tenocytes are mesenchyme-derived cells responsible for ...
Dynamic role of hyaluronan (HYA) in connective tissue activation and inflammation hyaluronic acidinflammationrejectionwound healingGerdin B, H盲llgren R (University Hospital, Uppsala, Sweden). Dynamic role of hyaluronan (HYA) in ... B Gerdin,R Hllgren - 《Journal of Internal Medicine》 被引量...
Immune-mediated inflammatory diseases (IMIDs) are characterized by excessive and uncontrolled inflammation and thrombosis, both of which are responsible for organ damage, morbidity and death. Platelets have long been known for their role in primary haemostasis, but they are now also considered to be ...
Integrins play a key role in cell proliferation, tissue repair, inflammation, infection, and angiogenesis. This review summarizes current evidence from human and animal studies on integrin structure and molecular signaling and promising role in diseases of inflammation, infection, and angiogenesis in ...
As one of the hallmarks of TME in tumorigenesis30, inflammation is mainly contributed by the immune cells together with tumor cells31. Among all immune cells being recruited to tumor sites, macrophages are in the majority and present as a special coordinator of multiple factors in the whole ...
In addition, a group of bioactive lipids, named specialized pro-resolving lipid mediators (SPMs), can be induced during inflammation and promote the resolution of inflammation, which are important for the recovery of tissue from inflammation. Failure of resolution owing to the reduced production of ...