Autoimmune connective tissue diseases are a group of disorders with heterogeneous clinical manifestations; however, they share one common feature, namely, inflammation of connective tissue. In some of these diseases, such as morphea or lichen sclerosus, the disease is limited to the skin, while in...
Rheumatoid arthritisis a disease in which the immune system attacks the thin membrane (called the synovium) lining the joints, causing joint pain, stiffness, warmth, swelling, andinflammationthroughout the body. Other symptoms may include:
The term connective tissue disease (CTD) refers to a large and heterogeneous group of immunologically mediated disorders characterised by inflammation, tissue damage and abnormal repair, often leading to degeneration of the target organ, replacement by fibrotic tissue and loss of function. These disorder...
Connective tissue disease(CTD) is a group ofsystemic autoimmune diseasescharacterized bychronic inflammationandfibrosisof the connective tissue that affects multiple organs and systems.Glucocorticoids(GCs) andimmunosuppressive agentsare commonly used in CTD treatment[1–3].However,immunosuppressive therapy, espe...
It is well documented that connective tissue disease (CTD) is a type of autoimmune disease characterized by chronic inflammation, which can occur across various organ systems throughout the whole body. Although the clinical manifestations of CTD are different, studies have shown that different CTD d...
Sjogren’s syndrome, is an autoimmune disorder that is associated with inflammation of the salivary glands in the mouth and the lacrimal glands in the eyes. Sjogren’s can be a primary condition, without any underlying connective tissue disease. It can be secondary to other CTDs, and is a ...
How is a connective tissue disorder diagnosed?You may have symptoms of several types of connective tissue disorders. This can make diagnosis difficult. Over time, you may develop one type of connective tissue disorder.Blood tests may be used to measure the amount of inflammation in your body or...
摘要: A connective tissue disorder characterized by immunological hyperactivity.Inflammation in multiple organs including skin and kidney.Three forms of lupus erythematosus (LE) -specific skin lesion: acute关键词: Humans Connective Tissue Diseases Diagnosis, Differential Rheumatology ...
Systemic inflammation promotes cardiovascular disease. Inflammatory connective tissue diseases (CTD) like lupus and rheumatoid arthritis associate with cardiovascular risk, but it is unknown whether particular groups of patients have enhanced propensity for atherosclerotic cardiovascular disease (ASCVD) associated...
Extracellular Matrix: Immunity and Inflammation Chapter© 2018 Connective Tissue Diseases: Introduction Chapter© 2022 Connective Tissue Diseases: Introduction Chapter© 2020 General References Alberts B, Bray D, Lewis J, Raff M, Roberts K, Watson JD (1994) Molecular biology of the cell. Garland...