We identified 190 RNA 5′rny_ends that could not be paired with 3′rny_ends, meaning that the RNA 3′ ends produced during the same processing events were not detected in the WT strain (Fig.5a, Supplementary Data1). In the comparisons described above, we observed that most of the 3′r...
(data not shown). Human kidney was labeled for RNase 7, nuclei and cell type markers. Cell type markers consisted of AQP-2 for principal cells, AE-1 for α-intercalated cells, and pendrin for β-intercalated cells. Isolated cells positive for RNase7 were identified in the collecting tubule...