Conflicts between RNA Polymerase II transcription and DNA replication are associated with increased DNA damage and genome instability. Nevertheless, how exactlyRojas, PatriciaWang, JianmingGuglielmi, GiovanniSadurnì, Martina MustèPavlou, LucasLeung, Ho...
去年和师兄讨论决定目前的方向是做RNA,这个和最近的病毒主题也有很多关系,毕竟RNA和疾病的发病是有关的。 在看文献遇到有的论文说positive-sense和negtive-sense,相关资料的说法是negtive-sense是编码序列的对称序列。那么positive-sense序列就一定都编码蛋白吗,还是说里面有非编码的。 留着这个问题,也许近期就能查到答案。
Novel RNA hybridization method for the in situ detection of ETV1, ETV4, and ETV5 gene fusions in prostate cancer The genetic basis of 50% to 60% of prostate cancer (PCa) is attributable to rearrangements in E26 transformation-specific (ETS) (ERG, ETV1, ETV4, and ETV5)... LP Kunju...
Significantly more ACPA-positive patients were RF-positive (P <0.001). Both ACPA-positive and ACPA-negative patients had median ages in the fifth decade, were mainly female, had severely active RA (median DAS28 scores >5.1) of a short duration and moderate disability (median HAQ scores 1.62)...
Kidney transplantation from a donor who is HCV antibody positive and HCV-RNA negative.doi:10.1016/S0041-1345(00)01572-4T.TokumotoandK.TanabeandT.SimizuandH.SDOSTransplantation Proceedings
(Mouse Brain Total RNA control, included in both SMART-Seq HT and SMART-Seq v4 kits).Panel B.Example results from one 293T cell (isolated using FACS).Panels C and D.Representative results generated from negative controls, showing either a totally flat profile (C) or a small number of ...
The switch from the synthesis of negative- to positive-strand RNA is thus regulated by NSP processing, which not only activates the efficient production of positive-strand RNA, but also disables negative-strand RNA synthesis. A mechanism for NSP translation, processing, and regulation of RV RNA ...
In answering this question, I will utilize two terms that used to demarcate sovereignty of states: positive and negative sovereignty. It is about 'sovereign to' and sovereign 'from'. I will also use two terms that differentiate two families of nation: the Great Powers and Outlaw States. In ...
Through various transplantation studies in mice, we show that CAFs in both invasive lobular breast cancer and triple-negative breast cancer originate from mammary tissue-resident normal fibroblasts (NFs). Single-cell transcriptomics, in vivo and in vitro studies reveal the transition of CD26+ and ...
Impact of combination therapies on HIV risk perceptions and sexual risk among HIV-positive and HIV-negative gay and bisexual men. The availability of improved HIV treatments may prompt reduced concern about HIV and sexual risk. Gay and bisexual men (N = 554, 17% HIV-positive) complete... P...