Navas S, Castillo I, Bartolome J, Marriott E, Herrero M, Carreno V: Positive and negative hepatitis C virus RNA strands in serum, liver and peripheral blood mononuclear cells in anti-HCV patients: relation with the liver lesion. J Hepatol 1994, 21:182-186....
Rubella virus (RV) genome encodes nonstructural protein (NSP) in a large open reading frame at its 5′ end. It is translated into p200 and further processed into p150 and p90. The NSPs are responsible for viral RNA replication, during which a full-length negative-strand RNA serves as the ...
去年和师兄讨论决定目前的方向是做RNA,这个和最近的病毒主题也有很多关系,毕竟RNA和疾病的发病是有关的。 在看文献遇到有的论文说positive-sense和negtive-sense,相关资料的说法是negtive-sense是编码序列的对称序列。那么positive-sense序列就一定都编码蛋白吗,还是说里面有非编码的。 留着这个问题,也许近期就能查到答案。
Impact of combination therapies on HIV risk perceptions and sexual risk among HIV-positive and HIV-negative gay and bisexual men. The availability of improved HIV treatments may prompt reduced concern about HIV and sexual risk. Gay and bisexual men (N = 554, 17% HIV-positive) complete... P...
Influenza A virus, a member of the Orthomyxoviridae virus family, is an enveloped, segmented, negative-strand RNA virus that encodes 11 proteins in the eight RNA segments encompassing its genome Chen et al 2001, Lamb and Krug 2001. WNV is an enveloped arbovirus with a single-stranded, 11-...
Eight virus families whose members infect vertebrates are currently known to possess single-stranded, positive-sense RNA genomes: the families Picornaviridae, Caliciviridae and Hepeviridae have non-enveloped capsids, whereas the families Flaviviridae, To
Persistence of HCV-RNA in a Blood Donor with Negative Antibody Assays We studied the sera from 21 healthy blood donors with positive HCV serology for a period of 2 years to evaluate HCV antibody dynamics and possible viremia... M Rapicetta,S Dettori,LA Kondili,... - 《Vox Sanguinis》 被...
In the replication cycle of a positive-strand RNA virus, the genomic positive stand is first copied into a negative strand genomic equivalent that serves as the template for the synthesis of more positive strands. Positive strand RNAs are needed in stoichiometric amounts to serve as mRNAs a...
Epstein–Barr virus (EBV)-associated gastric cancer exhibits distinct clinicopathologic characteristics, showing a good response to immune checkpoint inhibitors and a favorable prognosis. However, gastric cancer comprising distinct EBV-positive and -negative components in a single mass have been rarely repor...
A multivariate Cox regression analysis, including CD4 cell count, Centers for Disease Control and Prevention stage, age, sex, HIV RNA, highly active antiretroviral therapy and hepatitis C virus status, revealed that a high SENV DNA level was an independent risk factor or indicator for adverse ...