1997 . Positive and negative strand of hepatitis C virus RNA sequences in peripheral blood mononuclear cells in patients with chronic hepatitis C: No correlation with viral genotypes 1b 2a and 2b . J Med Virol 52 : 270 – 274 .Novoa LJ, Nagra RM, Nakawatase T, Edwards-Lee T, Tourtel...
Positive-strand RNA viruses include the majority of the plant viruses, a number of insect viruses, and animal viruses, such as coronaviruses, togaviruses, flaviviruses, poliovirus, hepatitis C, and rhinoviruses. Works from more than 50 leading laboratories represent latest research on strategies for...
Surprisingly, however, no dsRNA signals were detected for negative-strand RNA viruses. Thus, dsRNA is indeed a general feature of most virus groups, but negative-strand RNA viruses appear to be an exception to that rule. 展开 关键词: Hela Cells Vero Cells Animals Cercopithecus aethiops Humans ...
Negative-strand RNA virus A virus, the infectious virions of which contain the genome in a single-stranded, anti- messenger-sense RNA form. Retroplasmid A DNA plasmid that replicates by transcription and reverse transcription of an RNA intermediate. intracellular RNA-replication complexes of some, ...
Parallels among positive-strand RNA viruses, reverse-transcribing viruses and double- stranded RNA viruses. Nat Rev Microbiol. 2006 May; 4[5]:371-82. PMID: 16582931Ahlquist P. Parallels among positive-strand RNA viruses, reverse-transcribing viruses and double-stranded RNA viruses. Nat Rev ...
Here, we utilize unimolecular siRNAs that act as antiviral agents using an RNA polymerase I expression system. Expression of antiviral siRNAs abrogates RNA replication, antigen expression, and the production of infectious virus in segmented negative-strand RNA (influenza A virus) and nonsegmented ...
In the replication cycle of a positive-strand RNA virus, the genomic positive stand is first copied into a negative strand genomic equivalent that serves as the template for the synthesis of more positive strands. Positive strand RNAs are needed in stoichiometric amounts to serve as mRNAs an...
Rubella virus (RV) genome encodes nonstructural protein (NSP) in a large open reading frame at its 5′ end. It is translated into p200 and further processed into p150 and p90. The NSPs are responsible for viral RNA replication, during which a full-length negative-strand RNA serves as the ...
Deputy Section Editor:Roberto Bruzzone,Istituto Pasteur Italia, Italy ThePositive-strand RNA virusessection ofVirology Journalinvites submissions of research articles and reviews covering all aspects of positive-strand RNA virus biology. Basic research topics of interest include all facets of the viral lif...
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