RNA polymerase II contributes to preventing transcription-medi ated replication fork stalls. EMBO J 2015;34:236-50.Felipe-Abrio I, Lafuente-Barquero J, Garcia-Rubio ML, Aguilera A. RNA polymerase II contributes to preventing transcription-medi- ated replication fork stalls. EMBO J 2015;34:...
The polymerase produces RNA that is either coding for protein (messenger RNA) or noncoding RNA. At least four functional types of RNA exist: (1) Theribosomal RNA(rRNA) in the small subunit of a ribosome that scans mRNA in the 5′ to 3′ direction: Translation initiation inprokaryotesusually...
RNA-Dependent DNA PolymeraseReplicationAzidothymidineThere is considerable interest in the potential of human immunodeficiency virus type 1 (HIV-1) to develop ... BA Larder,SD Kemp,DJ Purifoy - 《Proc Natl Acad Sci U S A》 被引量: 1039发表: 1989年 Hepatitis C virus induces a mutator phenotyp...
The transcriptional machinery is thought to dissociate from DNA during replication. Certain proteins, termed epigenetic marks, must be transferred from parent to daughter DNA strands in order to maintain the memory of transcriptional states1,2. These pro
2023年5月16日，来自美国纽约大学医学院的Evgeny Nudler团队在Cell杂志发表了文章RNA polymerase drives ribonucleotide excision DNA repair in E. coli，他们通过冷冻电镜解析了RER与携带错误插入rNMPs的DNA双链的复合物结构，分析了RER对错误插入rNMPs的修复机制。研究人员首先在大肠杆菌中联合高亲和pull-down以及定量...
RNA polymerase, resulting in a 5′-FAD cap on the HCV RNA. The HCV FAD-capping frequency is around 75%, which is the highest observed for any RNA metabolite cap across all kingdoms of life. FAD capping is conserved...
Replication forks are impeded by DNA damage and protein-nucleic acid complexes such as transcribing RNA polymerase. For example, head-on collision of the replisome with RNA polymerase results in replication fork arrest. However, co-directional collision of the replisome with RNA polymerase has little...
Furthermore, 9458G in the JFH-1 variable region (VR) was responsible for RNA replication activity because of its RNA structures. In conclusion, N3H, high polymerase activity, enhanced kissing-loop interactions, and optimal viral RNA structure in the 3′UTR were required for J6CF replication in...
In subject area: Pharmacology, Toxicology and Pharmaceutical Science RNA dependent RNA Polymerase (RdRp) is an enzyme that is responsible for the replication of RNA from an RNA template. From: Bioorganic Chemistry, 2020 About this pageSet alert ...
DNA polymerase- the enzyme responsible for DNA replication RNA polymerase,transcriptase- the enzyme that copies DNA into RNA reverse transcriptase- a polymerase that catalyzes the formation of DNA using RNA as a template; found especially in retroviruses ...