RECENTLY ansystem for DNA replication has been described. This system could be divided into two fractions (A and B) both of which are necessary for proper DNA replication. Fraction A, the "soluble" fraction, contains those proteins which do not tightly bind to membranes or native DNA. ...
In mammalian cells, both semiconservative DNA replication and the DNA repair patch synthesis induced by high doses of ultraviolet radiation are known to be... SL Dresler,MG Frattini - 《Nucleic Acids Research》 被引量: 137发表: 1986年 Identification of DNA polymerase delta in CV-1 cells: stud...
Replication of DNA by DNA Polymerase ITemplate activity of DNA with DNA polymerase I is altered by the action of ionizing radiation. This is explained by the formation of new active and inactive enzyme binding sites on the DNA.R. SAFFHILLJ. J. WEISSNature New Biology...
A DNA polymerase involved in DNA replication in prokaryotes, is encoded by polB gene, and composed of 783 amino acids Supplement DNA polymerases are enzymes that assist in the replication of DNA. In prokaryotes, examples of these enzymes are DNA polymerases I, II, and III. The first known DN...
作为应对错配的第一道防线,复制中的DNA聚合酶(DNA polymerase)含有一个3'到5'的外切酶活性,使它们能够对新合成的DNA链进行校对(proofreading)[49]。这种外切酶活性能在DNA复制过程中纠正错误,通过改变聚合酶的方向并切除错误引入的核苷酸。即使校对能有效地纠正在DNA合成过程中产生的大多数错误,一些非沃森-克里克碱基...
(Proceedings of the National Academy of Sciences)发表了题为“DNA polymerase delta governs parental histone transfer to DNA replication lagging strand”的文章,该研究发现聚合酶δ(Pol δ)在DNA复制期间作为关键伴侣蛋白,将亲代组...
DNA 聚合酶(DNA polymerase)是细胞复制DNA 的重要作用酶。DNA 聚合酶是以DNA 为复制模板,四种脱氧核糖三磷酸为原料,将DNA由5'端点开始复制到3'端的酶。DNA聚合酶只能催化脱氧核糖核苷酸酸加到已有核酸链游离的3’-羟基上,所以需要引物链的存在。DNA 聚合酶是一种模板指导的酶,产物DNA性质完全不取决于聚合酶的来...
Three are devoted to the replication of the genome (DNA polymerases α, δ and ɛ); DNA polymeraseγ replicates the mitochondrial genome; and the rest are all devoted to the repair of specific types of lesion in DNA. There are, in addition, virally encoded DNA polymerases that replicate ...
Noun1.DNA polymerase- the enzyme responsible for DNA replication polymerase- an enzyme that catalyzes the formation of new DNA and RNA from an existing strand of DNA or RNA Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc. ...
DNA polymerase DNA聚合酶 DNA ligase DNA连接酶 在真核生物中没有DNA磷酸二酯酶的参与.AP内切核酸酶切除后,DNA聚合酶切除AP位点的磷酸戊糖并填补空隙。 不过,真核DNA聚合酶β没有原核DNA聚合酶I那样的3'→5'外切核酸酶活性,不能校正配对的错误。