2023年5月16日，来自美国纽约大学医学院的Evgeny Nudler团队在Cell杂志发表了文章RNA polymerase drives ribonucleotide excision DNA repair in E. coli，他们通过冷冻电镜解析了RER与携带错误插入rNMPs的DNA双链的复合物结构，分析了RER对错误插入rNMPs的修复机制。研究人员首先在大肠杆菌中联合高亲和pull-down以及定量质...
2023年5月16日,来自美国纽约大学医学院的Evgeny Nudler团队在Cell杂志发表了文章RNA polymerase drives ribonucleotide excision DNA repair in E. coli,他们通过冷冻电镜解析了RER与携带错误插入rNMPs的DNA双链的复合物结构,分析了RER对错误插入rNMPs的修复机制。 研...
Certain proteins, termed epigenetic marks, must be transferred from parent to daughter DNA strands in order to maintain the memory of transcriptional states1,2. These proteins are believed to re-initiate rebuilding of chromatin structure, which ultimately recruits RNA polymerase Ⅱ (Pol Ⅱ) to the...
Replication proteins encoded by bacteriophage T4 generate DNA replication forks that can pass a molecule of Escherichia coli RNA polymerase moving in the same direction as the fork in vitro . The RNA polymerase ternary transcription complex remains bound to the DNA and retains a transcription bubble ...
DNA polymerase- the enzyme responsible for DNA replication RNA polymerase,transcriptase- the enzyme that copies DNA into RNA reverse transcriptase- a polymerase that catalyzes the formation of DNA using RNA as a template; found especially in retroviruses ...
What is the role of RNA polymerase in protein synthesis? How are the structures of RNA and DNA similar? How are DNA replication and protein synthesis different? How do the different DNA nucleotides pair during DNA replication? What is the role of DNA polymerase in DNA replication?
in which DNA polymerase makes new DNA strands starting from the primers. The leading strand only needs one primer for DNA polymerase to begin, but the lagging strand needs multiple primers, and DNA polymerase adds multiple DNA pieces between them, known a...
DNA polymerase is an enzyme that functions in the process of DNA replication. It is also involved in the repair of mismatches that occur during replication and double strand break repair. Is RNA polymerase used in transcription? RNA polymerase is used to synthesize a strand of RNA called messeng...
It has been established that activities of RNA-polymerase, DNA-polymerase, DNA-methyltransferase, and sphingomyelinase in the liver nuclei isolated from newborn (2-day-old) rats are by 18, 25, 27, and 610%, respectively, higher than those in mature (6-month-old) rats. It has been al...
RNA polymerase locally opens the double-stranded DNA so that one strand of the exposed nucleotides can be used as a template for the synthesis of RNA, a process called transcription.Ineukaryotic cells, activator proteins (some transcription factor proteins) bind to pieces of DNA called enhancers....