Database of mammalian mRNA polyadenylation http://polya.umdnj.edu/ PseudoBase Database of RNA pseudoknots http://wwwbio.leidenuniv.nl/~Batenburg/PKB.html REDIdb An RNA editing database http://biologia.unical.it/py_script/search.html Rfam Non-coding RNA families http://www.sanger.ac.uk...
新平台RNAInter(RNA Interactome Database)以RAID v2.0为蓝本,从文献及30个以上RNA相关数据库中获取总条目超过4000万条的多种类型RNA互作数据,同时结合RNA编辑、定位、修饰、靶区域、结构以及同源互作等注释信息,为使用者提供更为全面和细致的数据资源,并提供各种搜索、查询以及图形展示等功能...
等同于双端150bp (PE150)测序大约需要6G-9G (Gbase,Gb碱基数)的数据量;例如,150bp X 2端 X 20M reads = 6000 M = 6G,这里的6G数据量跟你看到的fastq.gz或者fastq文件大小(gigabyte,GB)还不是一回事,实际文件大小和压缩比率还有关系;拿到原始序列的fastq.gz数据后,就可以对每个基因或转录本进行...
2.1 数据集 所有的数据都是公开并可以在GEO database, RMBase, and RADAR database三个数据库中获取的,并且将有瑕疵的数据都舍弃了,增加了模型的鲁棒性和可靠性。经过以上筛选,最终得到了20个转录组,从15个不同的实验里得到的12种RNA修饰的分类(如表1所示),涵盖了所有能通过基本方法检测出来的RNA修饰以及包含了...
confirming that endogenous ADAR edits sensor transcripts but that its activity is insufficient to mediate efficient sensing. In addition, we found that ADAR-mediated editing is specific: we did not detect substantial off-target editing of other nearby adenosine residues in the sensor. These data, co...
The publicly available Quartet RNA reference materials can also be used for further evaluation of emerging technologies as well as new areas of interest that are beyond gene expression levels, such as AS, RNA editing, gene fusion and epitranscriptomics. In addition, the Quartet RNA reference ...
Currently, RNA-editing is considered to be a key regulator that controls various cellular functions, such as protein activity, alternative splicing pattern of mRNA, and substitution of miRNA targeting site. DARNED, a public RDD database, reported that there are more than 300-thousands RNA-editing...
YM500 collects analysis results for miRNA quantification, for isomiR identification (incl. RNA editing), for arm switching discovery, and, more importantly, for novel miRNA predictions. Wetlab validation on > 100 miRNAs confirmed high correlation between miRNA profiling and RT-qPCR results (R = ...
With the advancement of sequencing technologies and bioinformatics, over than 170 different RNA modifications have been identified. However, only a few of these modifications can lead to base pair changes, which are called RNA editing. RNA editing is a u
RADAR: a rigorously annotated database of A-to-I RNA editing. Nucleic Acids Res. 42, D109–D113 (2014). Article CAS PubMed Google Scholar Zhang, R. et al. Quantifying RNA allelic ratios by microfluidic multiplex PCR and sequencing. Nat. Methods 11, 51–54 (2014). Article CAS Pub...