5. Pan H, Strickland A, Madhu V, Johnson ZI, Chand SN, Brody JR, Fertala A, Zheng Z, Shapiro IM, Risbud MV: RNA binding protein HuR regulates extracellular matrix gene expression and pH homeostasis independent of controlling HIF-1alpha signaling in nucleus pulposus cells.Matrix Biol2019, 7...
The RNA binding protein fused in sarcoma/translated in liposarcoma(FUS/TLS) has been implicated in familial amyotrophic lateral sclerosis(fALS).The structure and physiological function of FUS have yet to be better defined.The mechanisms by which the fALS mutations in FUS cause cellular dysfunction ...
This study developed a FUS chimera (FUSIBB) with a highly efficient anti-aggregation signal that is engaged by a nuclear import receptor, Importin beta. FUSIBB can mitigate aggregation and reduce expression of a neurodegeneration-linked protein, FUS. ...
(FUS),Ewing's sarcoma breakpoint region 1(EWSR1) and TATA-box binding protein associated factor 15 (TAF15)) to undergo homogenous spontaneous LLPS in physiological conditions. In this model, the number of polar-pi interactions directly contribute to the driving force (the exchange paramet...
与无膜细胞器的形成相关的蛋白主要包含低复杂度结构域,如DNA结合蛋白TDP-43(TAR DNA-binding protein 43),RNA结合蛋白FUS(fused in sarcoma)等。这些包含低复杂度结构域的蛋白可以通过动态组装形成应激颗粒,而应激颗粒非正常相转变形成淀粉...
试剂和工具 RNA干扰产品 小分子 产品详情 中文名称:人RNA结合蛋白FUS(FUS)蛋白 英文名称:Human RNA-Binding Protein FUS (FUS) Protein 品牌:Abbexa 货号:abx168102 规格:10 µg 价格: $246.5 产品说明书下载: 产品预定 >> 产品预定,提交订单信息之后,我们会第一时间与您取得联系 ...
A liquid-to-solid phase transition of the ALS protein FUS accelerated by disease mutation. Cell 162, 1066–1077 (2015). This article provides a rationale for disorders characterized by accumulation of amyloid fibres. Article CAS PubMed Google Scholar Bogaert, E. et al. Molecular dissection of...
Human RNA-binding protein FUS (FUS/TLS) ELISA Kit 供应商 Biomatik 产品货号 EKC35418 产品报价 ￥询价/96T 产品说明书 点击查看 购买方式 银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868。 产品新闻 背景资料
与无膜细胞器的形成相关的蛋白主要包含低复杂度结构域,如DNA结合蛋白TDP-43(TAR DNA-binding protein 43),RNA结合蛋白FUS(fused in sarcoma)等。这些包含低复杂度结构域的蛋白可以通过动态组装形成应激颗粒,而应激颗粒非正常相转变形成淀粉样纤维从而导致神经退行性疾病。因此研究FUS的液-液相分离调节机制对于理解蛋白...
3) RNA-binding protein RNA结合蛋白 1. T-STAR is anRNA-binding proteinthat has an RNA-binding domains and function region of tyrosine phosphorylation. 2,其表达产物为分子量约55kDa的Sam68样蛋白,是STAR(signaltransductionandactivatorofRNA)家族新成员,具有RNA结合蛋白特征性的结合位点和酪氨酸磷酸化功能域...