Factor V Leiden mutation is a common genetic risk factor for venous thrombosis. It has been documented in up to 65% of patients with unexplained venous thromboembolism. This genetic mutation is now known to be the most common inherited cause of activated protein C (APC) resistance. Recently, ...
Factor V Leiden mutation is a common genetic risk factor for venous thrombosis. It has been documented in up to 65% of patients with unexplained venous thromboembolism. This genetic mutation is now known to be the most common inherited cause of activated protein C (APC) resistance. Recently, ...
Another mutation, factor V Leiden, has been established as a common hereditary risk factor for venous thrombosis, but its role in arterial disease remains... Wolfgang,Lalouschek,and,... - 《Thrombosis Research》 被引量: 122发表: 1999年 Dural puncture and activated protein C resistance: risk ...
Irish,AB.The factor V Leiden mutation and risk of renal vein thrombosis in patients with nephrotic syndrome. Nephrology Dialysis Transplantation . 1997... AB Irish - Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Associati...
摘要: Factor V Leiden mutation is a risk factor for the development of thrombo-embolic episodes in pregnancy. A case is presented of a pregnant woman with repeated episodes of venous thrombosis with a complicated clinical course.关键词: Leiden mutation Pregnancy Thrombotic episodes ...
Factor V Leiden mutation is a recognized most prevalent genetic risk factor for venous thromboembolic disease. Factor V mutations, are known to potentiate the effect of MTHFR on deep vein thrombosis. The thermo labile variant of the MTHFR gene (C677T) increases the plasma homocysteine levels and...
Factor V Leiden (factor V Arg506Gln), the genetic defect underlying resistance to activated protein C, is the most common risk factor for venous thrombosis... FR Rosendaal - 《Blood》 被引量: 897发表: 1997年 The factor V gene A4070G mutation and the risk of venous thrombosis. The A4070G...
Dyslipidaemia is a major risk factor for cardio-vascular disease, as it promotes atherosclerosis. While cross-sectional studies have identified higher serum cholesterol amongst individuals with the A blood group, there is less evidence from prospective s
Predictive value of factor V Leiden and prothrombin G20210A in adults with venous thromboembolism and in family members of those with a mutation: a systematic review. JAMA. 2009;301(23):2472-2485. doi:10.1001/jama.2009.853ArticlePubMedGoogle ScholarCrossref 38. GOV.UK. Investigation of ...
Purpose: We sought to assess the benefits, risks, and personal utility of factor V Leiden mutation testing to improve pregnancy outcomes and to assess the utility of decision-analytic modeling for complex outcomes in genomics.Methods: We developed a model to evaluate factor V Leiden testing among...