泛素、E3泛素连接酶、环指结构、跨膜域E3泛素连接酶(ubiquitin ligase enzyme)能识别底物蛋白并将其泛素化,导致底物蛋白通过26S蛋白酶体进行降解,是调节蛋白水平的重要因子.植物E3泛素连接酶在调控激素响应,参与形态建成,抗病防御反应和非生物胁迫响应方面起着重要作用.RING(Really Interesting New Gene 1)家族是含环指...
cullin-RING ubiquitin ligase (CRL)家族是E3连接酶中最大的一类,整个网络包含约300个独特复合物,介导总蛋白泛素化的20%。从结构上看,CRL由cullin骨架蛋白(包括Cul1-3、Cul4A-B、Cul5、Cul7七种)以及与E2结合酶结合的RING结构域蛋白RBX1或RBX2构成。当类泛素化蛋白NEDD8共价结合到cullin C末端的WHB亚结构域时(...
［摘 要］ Ｅ３泛素连接酶（ｕｂｉｑｕｉｔｉｎｌｉｇａｓｅｅｎｚｙｍｅ）能识别底物蛋白并将其泛素化，导致底物蛋白通过２６Ｓ蛋白酶体进行降解，是调节蛋白水平的重要因子。植物Ｅ３泛素连接酶在调控激素响应、参与形态建成、抗病防御反应和非生物胁迫响应方面起着重要作用。ＲＩＮＧ（ＲｅａｌｌｙＩｎｔｅｒｅｓｔ...
关键词:植物病理学;RING;E3泛素连接酶;抗逆;抗病 中图分类号:S435.111 ThefunctionsofRING-typeE3ubiquitinligasefamilyin responsetoabioticandbioticstress LIDayong (InstituteofBiotechnology,FacultyofAgriculture,ZhejiangUniversity,Hangzhou310058) Abstract:TheRINGfamilyisthelargesttypeofE3ubiquitinligaseswhichisspecified...
We demonstrated the regulatory function of Cullin-RING E3 ubiquitin ligase 4 (CRL4) in neurite morphogenesis during early neurodevelopment. Cul4a and Cul4b, the core scaffold proteins of CRL4, exhibit high expression and activation within the cytosol of developing neurons, regulated by neuronal ...
The importance of E3 ubiquitin ligases from different families for plant immune signaling has been confirmed. Plant RING-type E3 ubiquitin ligases are members of the E3 ligase superfamily and have been shown to play positive or negative roles during the regulation of various steps of plant immunity...
Verticillium dahliae;ubiquitin ligase E3;histone ubiquitination;VdBre1;VdHrd1 1. Introduction The ubiquitination mechanism involves the consecutive actions of ubiquitin activating enzyme (E1), ubiquitin conjugating enzyme (E2), and ubiquitin ligase (E3), which attach ubiquitin to a target protein [1]....
RING1 | E3 ubiquitin-protein ligase RING1 供应商 Agrisera 产品货号 AS16-3829 产品报价 ￥询价/50ug 产品说明书 点击查看 购买方式 银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868。 产品新闻 背景资料 RING1 involved in protein ubiquitination. Alternative names: RING...
建议收到该E3 Ubiquitin-Protein Ligase RING1 (RING1) Antibody产品后,储存温度为-20°C。避免重复冻融其他 Abbexa总部位于英国剑桥的剑桥科学园,是一家专业的全球抗体供应商和蛋白质供应商,致力于为生命科学、药物开发和生物技术领域的科学家和研究者提供最佳的客户体验和高质量的产品。产品涵盖一抗、二抗、蛋白质...
Key words: plant pathology; RING; E3 ubiquitin ligase; stress resistance; disease resistance 0 引言泛素是一个由 76 个氨基酸残基组成的高度保守的多肽,广泛分布于各类细胞,被泛素标记的蛋白质将被特异性识别,其中多聚泛素化的蛋白将被特异性降解从而调控细胞周期,信号传导,DNA 修复,细胞凋亡等过程。而单泛素...