Gastric cancer derived exosomal THBS1 enhanced Vγ9Vδ2 T-cell function through activating RIG-I-like receptor signaling pathway in a N6-methyladenosine methylation dependent manner.Cancer Lett.2023 Sep 30:216410. doi: 10.1016/j.canlet.2023.216410. 文章转载分享,如有侵权,请联系删除。
The RLG-I like receptor signaling pathway plays an important role in preventing the body from being infected by viruses. For this immune defense, the virus has some strategies to interfere with this process. After a virus infects cells, it often destroys the transduction of the RLR signaling ...
【关键词】 RIG-I 样受体； 信号通路； 调控机制； 病毒感染； 免疫反应 doi：10.14033/j.cnki.cfmr.2019.14.086 文献标识码 A 文章编号 1674-6805(2019)14-0184-03 A Review of RIG-I Like Receptor Signaling Pathway and Its Regulation/DING Ruxuan.//Chinese and Foreign Medical...
本研究综述RIG-I样受体的多种信号通路和调控机制,为病毒感染的控制和免疫调节治疗提供新的思路和方向。 【关键词】RIG-I样受体;信号通路;调控机制;病毒感染;免疫反应 doi:10.14033/j.cnki.cfmr.2019.14.086文献标识码A文章编号1674-6805(2019)14-0-03 A Review of RIG-I Like Receptor Signaling Pathway and...
I and MDA5. For example, TRIM13 negatively regulates MDA5-mediated type I IFN production but positively regulates RIG-I signaling [83]. Except for ubiquitin, the ubiquitin-like protein FAT10 is recruited to RIG-I by ZNF598, resulting in the inhibition of RIG-I polyubiquitination and IFN ...
The RIG-I like receptor signaling pathway was found to be the major signal pathway that changed during HBV-related fibrosis. This study provides novel ... F Kan,L Ye,Y Tao,... - 《Bmc Genomics》 被引量: 2发表: 2017年 5′-triphosphate-siRNA逆转HBV诱导的NK细胞功能低下的机制研究 RIG-I...
RIG-I-like receptor signaling pathway Specific families of pattern recognition receptors are responsible for detecting viral pathogens and generating innate immune responses. Non-self RNA appearing in a cell as a result of intracellular viral replication is recognized by a family of cytosolic RNA helica...
RNA,activate the RIG-I signaling pathway,promote the production of cytokines and exert the antiviral effect.This study reviews the various signaling pathways and regulatory mechanisms of RIG-I like receptors,providing new ideas and directions for the control of viral infection and immunomodulatory ...
通过对RLR信号通路分子在抗病毒免疫调节中的作用了解,可以为控制病毒的感染和免疫调节提供一个新的思路。关键词:RIG-I样受体;先天性免疫;细胞信号转导;病毒感染中图分类号:S852.42文献标志码:A文章编号:1674-6422(2014)05-0072-08ADVANCESINSIGNALINGPATHWAYSANDREGULATIONOFRIG-I-LIKERECEPTORDINGYun-lei1,SUNYing-...
被感染的细胞 中,这种相互作用可以通过触发RL Rsv 2)~. 下游信号分子的活化,最终导致I 型干扰素的产生和炎性因 子的产生,细胞做 出抗病毒免疫应答。本文简单介绍了RL R信号通路的组成及其泛素化调控 ,总结了病毒逃避RL R 通路信号转 导的机制,最后阐述了NOD样受体 ( NOD. 1ike receptors,NLR s) 通路对RL...