Ribotoxic Stress Response ribotoxic的应激反应 Ribotoxic的应激反应
Ribotoxic stress drives cell death by UVdoi:10.1038/s41556-024-01506-8Petra GrossNature Cell BiologyNature Publishing Group UKNature Cell Biology
Ribotoxic stressEndoplasmic reticulum stressTrichothecenes are sesquiterpenoid mycotoxins commonly found as contaminants in cereal grains and are a major health ... C Arunachalam,FM Doohan - 《Toxicology Letters》 被引量: 188发表: 2013年 Mode of action of mycotoxins which binds to the eukaryotic ribo...
单词 Ribotoxic Stress Response 释义 SeeRSR 随便看 Federation of the European Societies of Chemotherapy and Infection Federation of the European Sporting Goods Industry Federation of the Hong Kong Polytechnic University Alumni Associations Federation of the Israel Societies for Experimental Biology Federation ...
Mechanistically, ribotoxic stress activates the JNK-USP36 signaling to stabilize Snail1 in the nucleolus, which facilitates ribosome biogenesis and tumor cell survival. Furthermore, we show that HHT activates the JNK-USP36-Snail1 axis in solid tumor cells, but not in leukemia cells, resulting in...
doi:10.1007/s00204-010-0581-1J. D. StewartH. M. BoltJ. G. HengstlerSpringer-VerlagArchives of ToxicologyStewart JD, Bolt HM, Hengstler JG (2010) Ribotoxic stress by mycotoxins. Arch Toxicol 84(9):661-662
Biochemistry Induction of ribotoxic stress response by mycotoxin deoxynivalenol| A proteomic view MICHIGAN STATE UNIVERSITY James J. Pestka PanXiaoThe trichothecene mycotoxin deoxynivalenol (DON) is a common food contaminant that is of public health significance (Pestka, 2010) because it is a ...
skinribotoxic stress responseZAK-alphapyroptosisapoptosisinflammationp38JNKSolar UVB light causes damage to the outermost layer of skin. This insult induces rapid local responses, such as dermal inflammation, keratinocyte cell death, and epidermal thickening, all of which have traditionally been associated...
We report here that ribotoxic stress triggers the assembly of the human pyrin inflammasome, leading to ASC oligomerization and caspase-1 activation in THP-1 macrophages and in a 293T cell line stably reconstituted with components of the pyrin inflammasome. Knockdown of pyrin and selective ...
Anisomycin, a well-known inducer of ribotoxic stress that activates both p38 and JNK, also activated PAI-1 gene expression, while other protein synthesis inhibitors that do not activate the kinases failed to do so. PAI-1 gene expression by 13-deoxytedanolide and anisomycin was blocked by SB...