Tandem Retro-Michael Addition-Claisen Rearrangement-Intramolecular Cyclization: One-Pot Synthesis of Densely Functionalized Ethyl Dihydropyrimidine-4-carboxylates from Simple Building Blocksretro-Michael additionClaisen rearrangementintramolecular cyclization
Studies on the reaction of some 1,5-ketodiesters/1,5-diketones with NaX (X = Cl/Br/I)/DMSO have shown that under microwave/thermal conditions, facile retro -Michael addition (RMA) reaction takes place instead of formation of the expected Krapcho products. Mechanistic studies have shown that...
Study of michael-michael-retro michael addition catalyzed by 9-amino-9-deoxyepiquinine using ESI-MSStudy of michael-michael-retro michael addition catalyzed by 9-amino-9-deoxyepiquinine using ESI-MSSpectroscopic databaseValidationWater vaporAtmospheric...
In the course of Michael addition of carbanions, derived from malononitrile or cyanoacetic ester, to a nitrostyrol retro reaction has also been observed. Depending on the reaction conditions any of the two compounds formed can be obtained as main product. The entire process has been thoroughly ...
Tetrahydrodiazepin-5-ones, when heated with HCl, are transformed by retro-Michael addition and recondensation into alkenylpyrazoles (Scheme 7) 〈84H(22)2265〉. Sign in to download full-size image Scheme 7. Asymmetric hydrogenation of 1,2-diacyl- and 1,2-bis(alkoxycarbonyl)-2,3,4,5-tetr...
本研究基于绿色合成,发展了催化的α,β-不饱和羰基化合物分别与苯并咪唑类杂环水相aza-Michael加成反应以及与芳香b-二酮的Michael addition/retro-Claisen condensation串联反应,从而高效合成新型苯并咪唑衍生物和1,5-二羰基酯类化合物.苯并咪唑类结构单元作为一类重要的含氮杂环,广泛应用于药物,超分子和有机功能材料...
单位代码10635学号11013316001159硕士学位论文-不饱和羰基化合物aza-Michaeladdition反应和Michael/retro-Claisencondensation串联反应的绿色合成研究论文作者:文静指导教师:蔡桂鑫副教授学科专业:有机化学研究方向:生物有机药物化学提交论文日期:016年04
A number of novel tandem sequences initiated by a retro-aldol process are described along with preliminary scope and limitation studies. These include (i) retro-aldol/Wittig trapping/intramolecular Michael addition, (ii) retro-aldol/aza-Wittig/intramolecular imine addition, (iii) retro-aldol/Henry/...
In addition, the addition of envelopes, handbags, leather shawls and thick bottom shoes also makes the overall design more colorful. < /p > < p > < strong > style > /strong > /p > < p > Michael Kors2014 spring and summer women's wear series is the inspiration for the 40s and 70...
(more than twice as many as the next guy - Billy Crystal) and headlined his own variety specials year after year. In addition to his own inimitable joke delivery, Bob became known for his snappy repartee with fellow comics (George Burns, Milton Berle, Jack Benny, Phyllis Diller, Danny Thom...