Characterization of neurons in the area of the medullary lateral reticular nucleus responsive to noxious visceral and cutaneous stimuli. Brain Res 802: 163-174, 1998.Ness TJ, Follett KA, Piper J, Dirks BA. Characterization of neurons in the area of the medullary lateral reticular nucleus ...
The neural mechanisms subserving recognition of noxious stimuli and empathy for pain appear to involve at least in part the cortical regions associated with the processing of pain affect. An important issue concerns the specificity of brain networks associated with observing and representing painful condi...
Strong noxious stimuli cause plastic changes in spinal nociceptive neurons. Intracellular signal transduction pathways from cellular membrane to nucleus, which may further regulate gene expression by critical transcription factors, convey peripheral stimulation. Cyclic AMP-responsive element binding protein (CREB...
Inflammation caused by noxious stimuli or injury is related with various diseases, such as inflammatory bowel disease, acute lung injury, cancer, and so on [1], [2], [3]. It has also been shown to have cross-talk with hypoxia, in fact, the concept that inflamed lesions usually become ...
Background Strong noxious stimuli cause plastic changes in spinal nociceptive neurons. Intracellular signal transduction pathways from cellular membrane to nucleus, which may further regulate gene expression by critical transcription factors, convey peripheral stimulation. Cyclic AMP-responsive element binding pr...
Characterization of neuronal responses to noxious visceral and somatic stimuli in the medial lumbosacral spinal cord of the rat. The cutaneous receptive fields, long ascending projections, and responses to colorectal distension (20-100 mmHg) and tail movement of 252 neurons in spinal... TJ Ness,GF...
The changed central synaptic plasticity may be initiated by activity-dependent intracellular biochemical pathways following noxious stimulation of the peripheral tissue [1-5].It has been extensively reported that extracellular signals conveyed and transduced through the plasma membrane to the intracellular ...
Strongnoxiousstimulicauseplasticchangesinspinalnociceptiveneurons.Intracellularsignaltransductionpathwaysfromcellularmembranetonucleus,whichmayfurtherregulategeneexpressionbycriticaltranscriptionfactors,conveyperipheralstimulation.CyclicAMP-responsiveelementbindingprotein(CREB)isawell-characterizedstimulus-inducedtranscriptionfactorwhose...
engineeringRetina nociceptor,as a key sensory receptor,not only enables the transport of warning signals to the human central nervous system upon its exposure to noxious stimuli,but also triggers the motor response that minimizes potential sensitization.In this study,the capability of two-dimensional ...
it is exposed to variousxenobioticsand is a major multifunctional organ responsible fordetoxificationand metabolism; consequently,ROSproduction is inevitable. Therefore, rapid and efficient antioxidant systems are present in the liver, such as the Nrf2 signaling pathway, to counteract the noxious effects ...