(2002). Proteinase-activated receptor-1 agonists attenuate nociception in response to noxious stimuli. Br. J. Pharmacol. 135, 1101-1106.SamuelAsfaha;ValentineBrussee;KevinChapman;Douglas;WZochodne;NathalieVergnolle.Proteinase‐activated receptor‐1 agonists attenuate nociception in response to noxious ...
constituting the first line of defense against infectious agents [24]. However, PRRs also play a role in sterile inflammation by responding to endogenous stimuli known as DAMPs or alarmins. Types of PRRs include
Evidence has accumulated that men and women show different responses to noxious stimuli, with women exhibiting greater sensitivity to pain than men. Data concerning sex differences in cortisol response patterns have revealed inconsistent results so far. The purpose of the present study was to examine ...
Conversely, participants who had been sleeping, and thus unaware of getting noxious heat, displayed heightened pain during the first part of the test-phase. This heightened reaction to noxious stimuli—a pain alarm response—was further pronounced in the control conditions where participants were nave...
The literature on the experimental response to noxious stimuli in patients with chronic pain has been reviewed and it has been shown that there are very few studies in this field either of "psychogenic" or "organic" pain. The results are then reported of investigations of the response to pin...
We discovered that the regulator of G protein signalling (RGS) protein, EGL-10, is required for appropriate avoidance responses to noxious stimuli sensed by ASH. As it does for other behaviours in which it is also involved, egl-10 interacts genetically with the Go/iα protein GOA-1, the ...
详细解释: 以下为句子列表: 英文: These results, combined with earlier work, suggest that a distress response to a noxious stimuli may be almost entirely subcortical, however, the finer discrimination and emotional overlay of this painful appreciation may be cortical in location (1). ...
Arrowheads point to the peaks of the recorded RGC Ca++ -transients, red dots mark PSTHτ values for each wave and the white and black areas of the bar below the recordings show the on- and offsets of the light stimuli. Clearly, both the response onsets and the decay time (slope) are...
Nociceptors are a subpopulation of dorsal root ganglia (DRG) neurons that detect noxious stimuli and signal pain. Veratridine (VTD) is a voltage-gated sodium channel (VGSC) modifier that is used as an “agonist” in functional screens for VGSC blockers. However, there is very little informati...
Gay men show altered psychobiological stress responses and exhibit a higher prevalence of mental disorders than their heterosexual counterparts. Both of these findings are likely due to gay-specific discrimination. Since it has not yet been determined whether gay-specific stress is more noxious than ...