Background Consistent evidence shows an impact of systemic haemodynamic overload on the right ventricle, but its functional and structural consequences have received scarce attention for several reasons including the difficult application of conventional imaging techniques due to the complex shape and orienta...
Wound healing and neutrophil activity biomarkers in patients with COVID-19. Note Healthy controls: n = 16, COVID-19: n = 63. Data were analysed with Mann Whitney test and shown as median with interquartile range Full size image Neutrophil activity biomarkers CPa9-HNE and ELP-3 ha...
T. New strategies for the next generation of matrix-metalloproteinase inhibitors: selectively targeting membrane-anchored MMPs with therapeutic antibodies. Biochem. Res. Int. 2011, 191670 (2011). PubMed Google Scholar Zeisberg, M. et al. Stage-specific action of matrix metalloproteinases influences ...
Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Member of the German Center for Lung Research (DZL), Hannover Medical School, Hannover, Germany Lars Knudsen & Matthias Ochs REBIRTH, Cluster of Excellence, Hannover Medical School, Hannover, Germany Lars Knudsen & Matth...
Radiofrequency ablation (RFA) represents a well-established and guideline-approved minimally-invasive therapy for patients with very early and early stage hepatocellular carcinoma (HCC)1,2,3. The efficacy of this potentially curative technique has been validated in randomized controlled clinical trials ...
Extensive studies provide a glimpse into the potential roles of Kpr in cancer diagnosis and therapy. The sharp reduction in Kpr of H3K23 in the U937 leukaemia cell line during monocytic differentiation implies that the initial hyperpropionylation in U937 cells might be a stage-specific marker duri...
Extensive studies provide a glimpse into the potential roles of Kpr in cancer diagnosis and therapy. The sharp reduction in Kpr of H3K23 in the U937 leukaemia cell line during monocytic differentiation implies that the initial hyperpropionylation in U937 cells might be a stage-specific marker duri...
Our data show IL-33 to be present in human tendon biopsies at the early stage of disease, while end-stage biopsies have significantly less IL-33 expression at the message and protein level supporting the concept of IL-33 as an early tissue mediator in tendon injury and subsequent tissue ...
In NSCLC, low MTDH protein expression was correlated with lymph node metastasis, TNM stage and decreased OS (P=0.001, 0.011 and 0.013, respectively). Overexpression of MTDH reduced anchorage-independent and -dependent growth through arresting cell cycle, inhibited migration and invasion in vitro and...
Metastasis is responsible for the major mortality in lung cancer, which is the leading cause of cancer-associated death in the world (Siegel et al, 2013). Approximately two-thirds of non-small cell lung cancer (NSCLC) patients are diagnosed at an advanced stage, and 30%–50% of the ...