Extracellular matrix remodeling in wound healing of critical size defects in the mitral valve leaflet. Heart Vessel. 2016;31(7):1186-95.Stephens EH, Nguyen TC, Blazejewski JG, et al. Extracellular matrix remodeling in wound healing of critical size defects in the mitral valve leaflet[J]. ...
aWound healing, a complex process involving different types of cells and growth factors, can be divided into the following four phases: coagulation, inflammation, proliferation, and remodeling.1 After wound formation, blood coagulation factors are immediately released to stop the bleeding and to induce...
Larjava Integrins in wound healing Adv Wound Care, 3 (2014), pp. 762-783 CrossrefGoogle Scholar [21] U.K. Saarialho-Kere, et al. Cell-matrix interactions modulate interstitial collagenase expression by human keratinocytes actively involved in wound healing J Clin Invest, 92 (1993), pp. ...
Vascular injury, such as angioplasty, induces a complex healing process that is analogous to generalized wound healing. Following initial injury, platelet thrombi and an acute inflammatory response occur, followed by cellular inhibition by monocytes/macrophages, proliferation of vascular smooth muscle cells...
The stained sections showed the reestablishment of the lamellar organization of the stromal collagen across the site of the incision; the fluorescence showed where the connective tissue that was present when the wound was made persisted, and thereby defined the limits of remodeling in the healing ...
WOUND healingCELL membranesAQUEOUS humorANTIBIOTICSFIBROBLASTSThe cornea plays an important role in transmitting light and providing protection to the eye, but is susceptible to injury and infection. Standard treatments for corneal wounds include topical lubricants, antibiotics, bandage contact lens, and ...
Furthermore, Endo180 siRNA reversed the force-induced increase in COL III expression and the decrease in COL I expression under mechanical stimuli. Previous study showed Endo180 was involved in re-epithelialization and connective tissue remodeling during wound repair process [27]. Moreover, Endo180 ...
The gut microbiota (GM) plays a crucial role in maintaining the overall health and well-being of the host. Recent studies have demonstrated that the GM may significantly influence bone metabolism and degenerative skeletal diseases, such as osteoporosis (OP). Interventions targeting GM modification, ...
PURPOSE: To investigate the changes induced by DisBa-01 on repair of wound healing after induced incisional hernia (IH) in rats. METHODS: Thirty two male albino rats were submitted to IH and divided into four experimental groups: G1, placebo control; G2, DisBa-01-treated; G3, anti-α...
Human mesenchymal stem cells have attracted interest in regenerative medicine and are being tested in many clinical trials. In vitro expansion is necessary to provide clinical-grade quantities of mesenchymal stem cells; however, it has been reported to cause replicative senescence and undefined dysfunctio...