(1996) Conserved motifs in prokaryotic and eukaryotic polypeptide release factors: tRNA-protein mimicry hypothesis. Proc. Natl Acad. Sci. USA, 93, 5443-5448.Ito,K., Ebihara,K., Uno,M. and Nakamura,Y. (1996) Conserved motifs in prokaryotic and eukaryotic polypeptide release factors: tRNA- ...
The release factor (RF) class of translation factors plays a key role in terminating prote... Y Nakamura,K Ito - 《Wiley Interdisciplinary Reviews Rna》 被引量: 64发表: 2011年 Solution Structure of the PABC Domain from Wheat Poly (A)-Binding Protein: An Insight into RNA Metabolic and ...
Canonical eukaryotic initiation factors determine initiation of translation by internal ribosomal entry Mol. Cell. Biol, 16 (1996), pp. 6859-6869 Google Scholar 8. T.V. Pestova, I.N. Shatsky, S.P. Fletcher, R.J. Jackson, C.U. Hellen A prokaryotic-like mode of cytoplasmic eukaryotic ribo...
Although eRF1 is the functional counterpart of prokaryotic RF1 and RF2, the protein is unrelated in primary structure to the prokaryotic proteins and functions as an omnipotent release factor, decoding all three stop codons (23, 29, 19). Class 2 factors (RF3 and eRF3) are GTP-binding ...
The total number of prokaryotic representatives of the VLRF1 clade in the non-redundant database (NCBI, as of 1 December 2017) is 1,044. Of these, the archaeal VLRF1 family (aVLRF1) has 279 members, actino-chloroflexi VLRF1 family (acVLRF1) has 669 and the bacteroidetes VLRF1 family ...
Bacterial peptide chain release factors: conserved primary structure and possible frameshift regulation of release factor 2 Escherichia coli peptide chain release factors are proteins that direct the termination of translation in response to specific peptide chain termination co... WJ Craigen,RG Cook,WP ...
of atoms Protein Ligand/ion Water B-factors Protein Ligand/ion Water r.m.s. deviations Bond lengths (Å) Bond angles (°) PDB ID 50–2.73 99,064 20.5/23.2 26,653 137 299 55.37 47.81 38.22 0.004 0.872 – 50–3.25 62,128 20.9/24.5 25,976 68 33 83.02 57.03 52.84 0.003 0.673 5KNB...
1. A recombinant cell for overexpressing one or more proteins comprising one or more release factors. 2. The recombinant cell of claim 1 , wherein the cell is prokaryotic. 3. The recombinant cell of claim 2, wherein the prokaryotic cell is an E.coli cell. 4. The recombinant cell of cl...
prokaryotic release factor 1tRNA mimicry hypothesisTranslation termination requires two codon-specific protein-release factors in prokaryotes and one factor in eukaryotes. The underlying mechanism for stop codon recognition, as well as the biological meaning of the conservation of one or two release ...
Independently, the role of prokaryotic RF1/2 in GTPase activity of RF3 has been deciphered, as well as RF3 function itself.doi:10.1093/emboj/cdg017Lev KisselevMÃ¥ns EhrenbergLudmila FrolovaJohn Wiley & Sons, Ltd.Embo JournalTermination of translation: interplay of mRNA, rRNAs and release...