The endothelial cells which line the blood vessels as a monolayer exert a remarkable control over the vascular system. Indeed, the endothelium can be regarded as a highly active metabolic and endocrine organ in its own right. On the hand, vasoactive substances such as serotonin and bradykinin ...
These cells most likely regulate growth and differentiation, as well as the secretory functions of the prostate. Prostatic carcinoma exhibits neuroendocrine differentiation in 3 forms: 1) small cell neuroendocrine carcinoma, 2) carcinoid-like tumors and 3) conventional prostatic adenocarcinoma with focal ...
- 《American Journal of Reproductive Immunology》 被引量: 237发表: 2011年 Bidirectional interaction between the central nervous system and the immune system We believe that any questions regarding whether the CNS can alter immune system functions no longer remain. It can conclusively be stated that ...
Biontech’s $1.26B vaccine royalty settlement clears path forward
There might be SREBP functions beyond their involvement in sterol metabolism. Genome-wide and model organism approaches indicate that SREBPs coordinate cellular lipid metabolism with other cellular physiological processes that are broadly related to each other, such as cellular adaptations to environmental ...
CY-09 is another inhibitor of NLRP3, which functions directly and selectively. In both surgical mice OA models and in vitro cultured chondrocytes, CY-09 attenuated TNF-α induced inflammatory stress and showed therapeutic effects in cartilage degeneration [165]. Wedelolactone phosphorylated Ser/Thr in...
Behle et al., "Effects of glucagon-like peptide 1 on counterregulatory hormone responses, cognitive functions, and insulin secretion during hyperinsulinemic, stepped hypoglycemic clamp experiments in healthy volunteers," Journal of Clinical Endocrinology and Metabolism, vol. Hypoglycemia induced by insulin ...
Diabetes mellitus is a disease in the glucose-insulin endocrine metabolic regulatory system, in which the pancreas either does not release insulin or does not properly use insulin to uptake glucose in the plasma, which is referred as hyperglycemia. Complications of diabetes mellitus include retinopathy...
Emerging functions of regulatory T cells in tissue homeostasis. Front. Immunol. 9, 883 (2018). PubMed PubMed Central Google Scholar Levine, A. G., Arvey, A., Jin, W. & Rudensky, A. Y. Continuous requirement for the TCR in regulatory T cell function. Nat. Immunol. 15, 1070–1078...
TERT maintains the length of telomeres at the ends of chromosomes to maintain cellular functions, such as proliferation and cell cycle progression [75]. Mutations in the TERT promoter activate TERT transcription, which is responsible for the origination of PTCs arising from differentiated cell types....