Neurosciences Mechanisms of R-type calcium channel regulation in the enteric nervous system MICHIGAN STATE UNIVERSITY James J. Galligan NaidooVinogranThe enteric nervous system (ENS) regulates gastrointestinal function, and calcium channels are crucial to ENS function. There are distinct classes of ...
Vascular heat shock protein expression in response to stress. Endocrine and autonomic regulation of this age-dependent response. Adaptation to stress requires coordinated interactions between the vascular and endocrine systems. Previously we demonstrated that restraint stress induces... R Udelsman,MJ Blake...
and reduced high dense lipoprotein cholesterol (HDL), is typically observed in T2DM [11]. Mitochondrial dysfunction, ER stress, inflammation, abnormal fatty acid regulation, and β-oxidation may all be involved in dyslipidemia [12,13]. Excessive dietary intake of free fatty ...
First study assigning to IL-1β a physiological role in the regulation of insulin secretion. Article PubMed CAS Google Scholar Ellingsgaard, H. et al. Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells. Nat. Med. 17, 1481...
“pancreatic islets”, “insulin release”, “insulin secretion”, “diabetes”, “type 1 diabetes”, “type 2 diabetes”, “pathogenesis”, “histology”, “transcriptome”, “genetics”, “candidate genes”, “islet gene regulation”, “islet epigenomics”, “endoplasmic reticulum stress” and ...
摘要: THE ROLE OF HUMAN TYPE II GNRH RECEPTOR GENE IN THE REGULATION OF CELL PROLIFERATION KANAHO Yoh-Ichiro , ENOMOTO Masahiro , UTSUMI Mari , KATO Tomoko , PARK Min Kyun Proceedings of the Japan Society for Comparative Endocrinology (21), 68, 2006-11-03...
AD, T2D and AET can regulate the expression of microRNAs (miRNAs). Here, we review some of the changes in miRNAs expression regulated by AET, AD and T2D. MiRNAs play an important role in the gene regulation of key signaling pathways in both pathologies, AD and T2D. MiRNA dysregulation is...
The regulation of CNP release has been extensively studied using cultured endothelial cells, and CNP secretion is enhanced by TGF-β, TNF-α, IL-1, ANP, and sheer stress, and suppressed by insulin and VEGF. Unlike ANP, CNPs are not stored in large secretory granules. Receptors The ...
DNA methylation analysis is used to gain relevant knowledge about gene regulation and detect potential biomarkers. In this study, MethSurv74 and UALCAN75 were employed to investigate the DNA methylation status of sKGs. DNA methylation level was expressed as β-values (which ranged from 0 to 1)....
4b, c. Interestingly, the exercise training-induced fiber-type-specific regulation of these proteins was independent of their PRE-training expression. For example, while expression of CKB was approximately 23-fold higher in slow- than in fast-twitch fibers PRE training, it exhibited a greater ...