The stabilization of presynaptic inputs by AMPA receptors is not dependent on receptor-mediated current and instead relies on structural interactions mediated by the N-terminal domain of the glutamate receptor 2 (GluR2) subunit. These observations indicate that transsynaptic signaling mediated by the ...
Gisiger V. ( 1998 ) Regulation of gene expression by trans-synaptic activity: a role for the transcription factor NF-kappa B . J. Physiol. Paris 92 , 163 – 166 .Gisiger V. (1998) Regulation of gene expression by trans-synaptic activity: a role for the transcription factor NF-kappa B...
Neurotransmitters are released by Ca 2+ -triggered exocytotic fusion of synaptic vesicles. Before fusion, vesicles dock at a specialised presynaptic plasma membrane region, the active zone, where they are primed to a fusion competent state. The nature of this priming reaction has long been enigmatic...
Evidence is presented indicating that the initiation of mammalian puberty requires an array of transsynaptic and glial-neuronal interactions, brought about by neurons using excitatory and inhibitory amino acids as transmitters and astroglial cells producing cell-cell signaling molecules able to regulate neur...
(LGG). Based on the analysis of biological functions, we found thatGPX7might be involved in immune mechanisms involving both innate and adaptive immunity, type I interferon production and regulation of synaptic transmission in LGG, whereas in GBM, it is mainly related to metabolic regulation of ...
et al. The thalamus regulates retinoic acid signaling and development of parvalbumin interneurons in postnatal mouse prefrontal cortex. eNeuro 6, ENEURO.0018-19.2019 (2019). Article PubMed PubMed Central Google Scholar Aoto, J. et al. Synaptic signaling by all-trans retinoic acid in homeostatic ...
Intracellular and trans-synaptic regulation of glutamatergic synaptogenesis by EphB receptors. The majority of mature excitatory synapses in the CNS are found on dendritic spines and contain AMPA- and NMDA-type glutamate receptors apposed to presynap... MS Kayser,AC Mcclelland,EG Hughes,... - 《...
DNA methylation controls the timing of astrogliogenesis through regulation of JAK-STAT signaling Development, 132 (15) (2005), pp. 3345-3356 Google Scholar [100] N.H. Nguyen, et al. Propionate increases neuronal histone acetylation, but is metabolized oxidatively by glia. Relevance for propionic...
(Supplementary Data17). For instance, in the comparison of “0 d vs. 7 d”, cerebellum-specific DEGs were associated with synaptic signaling (e.g.,NTNG1,TNF,andGABBR2) and regulation of the cellular response to stress (HIF1A,ATF4,andPARG), while colon-specific DEGs were involved in ...
ABSENCE OF TRANSSYNAPTIC BETA ADRENERGIC RECEPTOR REGULATION IN OVINE FETAL LUNG AND HEARTPediatric Research publishes original papers, invited reviews, and commentaries on the etiologies of diseases of children and disorders of development, extending from molecular biology to epidemiology. Use of model ...