Regulation of stem cell differentiation in adipose tissue by chronic inflammation. Clin Exp Pharmacol Physiol 2011; 38(12): 872–878Ye J, Gimble JM (2011) Regulation of stem cell differentiation in adipose tissue by chronic inflammation. Clin Exp Pharmacol Physiol 38:872-878...
Epigenetic Regulation of Stem Cell Differentiation HAO WU, AND YI EVE SUN Departments of Molecular and Medical Pharmacology and Psychiatry and Behavioral Sciences, Neuropsychiatric Institute, University of California, Los Angeles, School of Medicine, Los Angeles, CA 90095 ABSTRACT: Stem cells undergo ...
Defining Developmental Potency and Cell Lineage Trajectories by Expression Profiling of Differentiating Mouse Embryonic Stem Cells Biologists rely on morphology, function and specific markers to define the differentiation status of cells. Transcript profiling has expanded the repertoir... A Kazuhiro,N Timur...
Utilizing a novel, in vitro, transwell-based coculture system, murine small intestinal stem cells were isolated and cultured with ENS neurons and glia or subepithelial myofibroblasts. Results show that the ENS contributes to regulation of intestinal stem cell fate, promoting differentiation into ...
ATP-independent mitochondrial activity is important for stem cell maintenance. Mitochondria are classically known as the essential energy producers in cells. As such, the activation of mitochondrial metabolism upon cellular differentiation was deemed a necessity to fuel the high metabolic needs of different...
One of the major issues in tissue engineering is regulation of stem cell differentiation toward specific lineages. Unlike biological and chemical signals, physical signals with adjustable properties can be applied to stem cells in a timely and localized manner, thus making them a hot topic for resea...
In this review, the roles of TGF-β family signals in coordinating ES cell fate determination are summarized. 展开 关键词: embryonic stem cell TGF-β BMP Activin Nodal self-renewal differentiation DOI: 10.1007/s11427-010-0096-2 被引量: 97 ...
We reported previously that stem cells associated with adult rat testis seminiferous tubules are able to give rise to differentiated Leydig cells in vitro. The regulatory mechanisms by which they do so, however, are uncertain. Herein, we hypothesized that the proliferation and differentiation of Leydi...
this indicates the important role of miRNA let-7 upon stem cell differentiation. Decreased level of let-7 has resulted in higher expression ofHMGA2, which induces self-renewal. Additionally,LIN28can acts independently of the let-7 family and contributes to self-renewal [95,96].(c)Adult HSCs...
Geometric cues for directing the differentiation of mesenchymal stem cells. Proc. Natl Acad. Sci. USA 107, 4872–4877 (2010). This study identifies surface topography as a regulator of stem cell differentiation. Article CAS PubMed PubMed Central Google Scholar Adamo, L. et al. Biomechanical ...