Protein phosphatases and the regulation of MAP kinase activity. Seminars in Cell and Developmental Biology 9: 143 -152.Keyse SM (1998) Protein phosphatases and the regulation of MAP kinase activity. Cell Dev Biol 9:143-152.Keyse S. Protein phosphatases and the regulation of MAP kinase ...
Identification of features regulating OST1 kinase activity and OST1 function in guard cells. Plant Physiol. 141, 1316–1327 (2006). Article CAS PubMed PubMed Central Google Scholar Vlad, F. et al. Phospho-site mapping, genetic and in planta activation studies reveal key aspects of the ...
AMP-activated protein kinase (AMPK) is a master regulator of cellular energetics which coordinates metabolism by phosphorylating a plethora of substrates throughout the cell. But how AMPK activity is regulated at different subcellular locations for precise spatiotemporal control over metabolism is unclear...
Overexpression of WRKY70, on the one hand, resulted in constitutive expression of SA-responsive PR genes, and on the other hand, caused repression of JA-responsive PDF1.2 gene [45]. Likewise, mpk4 (MAP kinase 4) knock-out mutants in Arabidopsis that exhibited constitutive SAR had higher ...
MAP kinases and their regulators are critical components of eukaryotic signaling pathways implicated in normal cell behavior as well as abnormal behaviors linked to diseases such as cancer. The mating pathway of the yeast Saccharomyces cerevisiae was central in establishing the MAP kinase paradigm. Here...
Geiger D, Scherzer S, Mumm P et al (2009) Activity of guard cell anion channel SLAC1 is controlled by drought-stress signaling kinase-phosphatase pair. Proc Natl Acad Sci USA 106:21425–21430. https://doi.org/10.1073/pnas.0912021106 Article PubMed PubMed Central CAS Google Scholar Gong ...
Kohorn BD, Johansen S, Shishido A, Todorova T, Martinez R, Defeo E, Obregon P (2009) Pectin activation of MAP kinase and gene expression is WAK2 dependent. Plant J 60:974–982. https://doi.org/10.1111/j.1365-313X.2009.04016.x Article CAS PubMed PubMed Central Google Scholar Koini...
A Mechanism for Cell-Cycle Regulation of MAP Kinase Signaling in a Yeast Differentiation Pathway. Cell. 2007;128:519-31 87. Zacchi P, Gostissa M, Uchida T, Salvagno C, Avolio F, Volinia S. et al. The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic ...
In addition, both drugs directly induced the phosphorylation of p44 and p42 MAP kinase, which was abolished by the specific inhibitors of MAP kinase activation, PD98059 and U0126. These data suggest a novel pharmacological mechanism whereby these ChE inhibitors regulate the secretory processes of ...
43,44 Integrin aggregation leads to the recruitment and phosphorylation of FAK, which provides a platform for various intermediate proteins (such as MAPK/ERK, JNK, Src kinase, and GTPases) to activate signaling pathways and mediate mechanical signal transduction (Fig. 3a).45 For example, ...