Regulation of humoral immunity by complement . Immunity (2012) 37 :199–207.10.1016/j.immuni.2012.08.002 [ Cross Ref ]Carroll MC, Isenman DE (2012) Regulation of humoral immunity by complement . Immunity 37 : 199–207 [ PubMed ]Carroll MC, Isenman DE. Regulation of humoral immunity by ...
The role of CD40 in the regulation of humoral and cell-mediated immunity ☆AnimalsHumansB-LymphocytesT-Lymphocytes, Helper-InducerMembrane GlycoproteinsCD40 LigandAntigens, CD40Antigens, CD80Antigens, Differentiation, B-LymphocyteCell Communication
Th2 cells produce cytokines such as IL-4, IL-5, and IL-13 to enhance humoral immunity and eliminate worms and other extracellular pathogens, which are the drivers of pathological allergic reactions [12]. Th17 cells control the transcription of IL-17 to promote the recruitment and activation ...
The serum complement system, which represents a chief component of innate immunity, not only participates in inflammation but also acts to enhance the adaptive immune response. Specific activation of complement via innate recognition proteins or secreted
Antibodies have glycosylation-dependent regulatory effect on inflammation. Therefore, PTX3, which is an essential component of humoral innate immunity, and immunoglobulins share functional outputs, including complement activation, opsonization and, as shown here, glycosylation-dependent regulation of ...
Tight regulation of B-cell activity is required to ensure humoral immunity against pathogens, on the one hand, and to avoid detrimental autoreactivity, on the other. Activation of B cells is mediated through cross-binding of the B-cell antigen receptor (BCR) and is greatly enhanced by co-...
Th2 cells promote the humoral immunity suppressing the cellular immunity.3.Immunoregulation on cellular levelTreg3.Immunoregulation on cellular levelTreg3.Immunoregulation on cellular levelB cell Reg 10、ulatory B cells (Bregs) a newly described subset of B cells, have been proved to play a ...
regulating both the nature of the response (humoral versus cellular immunity) and, in some cases, even whether a response occurs at all (activation versus anergy). This has been the subject of recent reviews by Fearon and Locksley (Science1996; 272:50-54) and Trinchieri and Gerosa (J. Leu...
As for humoral immunity, females are consistently found to possess a greater number of B cells (Abdullah et al., 2012), higher basal levels of immune globulin M (IgM) (Butterworth et al., 1967), and a stronger antibody response upon vaccination than males (Figure 1) (Furman et al., ...
These findings also lead to at least two possibilities as to the cause of renal lesions in RF/J mice: (1) the activation of systemic humoral immunity, which induced high serum levels of immunoglobulins and sequential immune-complex formation, and (2) specific response of local glomerular ...