The onset of pharmacological action of metoclopramide is 1 to 3 minutes following an intravenous dose, 10 to 15 minutes followingintramuscularadministration, and 30 to 60 minutes following an oral dose; pharmacological effects persist for 1 to 2 hours. ...
Gastroparesis (gastric stasis) may be responsible for poor diabetic control in some patients. Exogenously administered insulin may begin to act before food has left the stomach and lead to hypoglycemia. Because the action of metoclopramide will influence the delivery of food to the intestines and thu...
Onset: 1-3 min (IV, ); 10-15 min (IM); 30-60 min (PO) Duration: 1-2 hr regardless of route Peak serum time: IV, 15 min; PO, 60-120 min Distribution Protein bound: 30-40% Vd: 3.5 L/kg Metabolism Metabolized by liver ...
Action - antiemetic- stimulates peristalsis, decreases n/v, decreases symptoms of gastric stasis Indications - post-op/diabetic gastric stasis- GERD- post-op n/v Dose 10-15 mg Diluent - may dilute to 0.2 mg/mL or give undiluted at 5 mg/mL Administration Time 1-2 min Onset, Peak, Durati...