Enantioselective reduction of aryl ketones using LiBH4 and TarB-X:a chiral Lewis acid. Suri, J. T,Vu, T,Hernandez, A,Congdon, J,Singaram, B. Tetrahedron Letters . 2002Enantioselective reduction of aryl ketones using LiBH 4 and TarB-X: a chiral Lewis acid[J] . Jeff T Suri,Truong Vu...
Suri,J.T,Vu,T,Hernandez,A,Congdon J,Singaram,B.Enantioselective reduction of aryl ketones using LiBH4 and TarB-X:a chiral Lewis acid. Tetrahedron Letters . 2002SURI J T, VU T, HERNANDEZ A, et al. Enantioselective reduction of aryl ketones using LiBH4 and TarB-X: a chiral Lewis acid...
The catalytic performance of the partially purified reductase was examined, and the highest activity was observed at pH 6.5 and 50 °C. The short-chain alkyl aldehydes such as acetaldehyde and those aldehydes or ketones with a benzoyl group were found to be good substrates for the reductase. ...
The current methodology substantiates a promising and alternative green approach for the synthesis of secondary chiral alcohols of biological importance in a mild, cheap and environmentally benign process.Keywords: Plant cell suspension culture,(S)-1-arylethanols,arylketones,enantioselective bioreduction,...
Reduction of α,β-unsaturated ketones generally can give rise to a variety of products, of which chiral allylic alcohols (1,2-reduction) and saturated ketones (1,4-reduction) are the most useful from the synthetic point of view. With the appropriate substitution pattern these processes generate...
- 《Journal of the American Chemical Society》 被引量: 160发表: 1984年 ASYMMETRIC REDUCTION OF KETONES TO FORM OPTICALLY ACTIVE ALCOHOLS A process for producing optically active secondary alcohols by reducing an optically inactive ketone in the presence of an optically active Group VIII metal ...
If metalloenzymes could react through abiotic intermediates like these, then the scope of enzyme-catalysed reactions would expand. Here we show that zinc-containing carbonic anhydrase enzymes catalyse hydride transfers from silanes to ketones with high enantioselectivity. We report mechanistic data ...
One of the first studies in biocatalysis developed in Brazil employed Saccharomyces cerevisiae for the reduction of ketones. These works were reported in the beginning of the 1990s by Rodrigues and Moran (Brenelli et al., 1990; De Carvalho et al., 1991). After that, a number of studies eme...
Reductions of aryl ketones (69; equation 30) using (excess) isopropyl alcohol as hydrogen donor and at partial conversions have led to the formation of alcohol (70) in modest enantiomeric excesses with various chiral ligands.54–57 (30) Metal carbonyls like Mo(CO)6 or Mn2(CO)10 will ...
A re-examination of the reduction of aryl alkyl ketones by zinc–aluminum chloride.Pinacol reduction-cum-rearrangement. A re-examination of the reduction of aryl alkyl ketones by zinc–aluminum chloride.Reduction of alkyl phenyl ketones by zinc and aluminum chloride in acetonitrile results in pinacol...