During recovery from treatment with puromycin and 5-fluorouracil, particles are formed; however, the component corresponding to the 50-S ribosomes appears lighter than normal in the sucrose gradient (and total ribosome formation is greatly inhibited). 3. 3. If RNA is allowed to accumulate in ...
We evaluated the effect of royal jelly (RJ) on 5-fluorouracil (5-FU)-induced oral mucositis in hamsters. Oral mucositis was induced in hamsters through a combination of 5-FU treatment and mild abrasion of the cheek pouch. RJ was contained in chitosan-sodium alginate film (RJ film). Films...
Transgenic mice overexpressing human c-mpl ligand exhibit chronic thrombocytosis and display enhanced recovery from 5-fluorouracil or anti-platelet serum treatment. Blood 1997; 89: 1551-1559.Transgenic mice overexpressing human c-mpl ligand exhibit chronic thrombocytosis and display enhanced recovery from ...
(2008). Systemic 5-fluorouracil treatment causes a syndrome of delayed myelin destruction in the central nervous system. Journal of Biology, 7(4), 12. doi:10.1186/jbiol69. Article PubMed PubMed Central Google Scholar Harrison, D. M., Caffo, B. S., Shiee, N., Farrell, J. A., ...
Treatment of murine bone marrow cells with the cytotoxic agent 5-fluorouracil (5-FU) results in the release of a nondialyzable inhibitor of progenitor (colony-forming unit-granulocyte macrophage; CFU-GM) proliferation. When murine bone marrow cells were treated with 5-FU plus LSF, release of ...
We examined the role of the p53 tumor suppressor gene in hematopoietic recovery in vivo after treatment with the cytotoxic drug 5-fluorouracil (5-FU). We used p53 knock-out (p53-/-) and wild-type (p53+/+) mice injected with 5-FU as the experimental model. Analysis of the repopulation ...
This study evaluated the usefulness of the Experiential Focusing Method as apsychological tool in the treatment of cancer patients. The researchers measured the impact of focusing on depression, hardiness, body cathexis, body attitudes andphysical activity level for twelve cancer patients (eleven women ...
and desiccation "C&D" (scrape and burn), cryosurgery (specialized deep freezing), photodynamic therapy using Levulan and laser and or blue light, regular surgical excision, laser removal and surgery, Mohs surgery, and several prescription creams, including imiquimod (Aldara) and fluorouracil (Efudex)...
Solid tumour models for the assessment of different treatment modalities: IV. the combined effects of radiation and 5-fluorouracil. Neither radiation alone (375 to 1500 rad) nor5-fluorouracil (FU) alone (50-250 mg/kg) is sufficient to prevent an increase in the volume of the solid tumou.....
Foster R, Frelick R, Lerner H, Levitt M, Margolese R, MacFarlane J, Plotkin D, Shibata H, Volk H (1977) l-Phenylalanine mustard (l-PAM) in the management of primary breast cancer: An update of earlier findings and a comparison with those utilizing l-PAM plus 5-fluorouracil (5-FU)....