At present, the antifibrotic drugs 5-fluorouracil and mitomycin C are used to modulate healing, although there is risk of serious side effects due to their toxicity. The potential of a lectin from the edible mushroom Agaricus bisporus as a less toxic modulator of wound healing has been ...
the efficacy of dressings was evaluated over a time-course of 7, 14 or 21 days. Sterile formulations were applied once to the wound defect area immediately after the surgery using a sterile transparent barrier (e.g., Tegaderm®), an antibiotic-impregnated...
First Affiliated Hospital of Medical School, Xi-an Jiaotong University, Xi-an 710004, China Aim: The aim of the study was to evaluate the outcome of adenovirus-mediated p27KIP1 (Ad-p27) expression on wound heal- ing after filtration surgery and to investigate the inhibition of cell prolifera...
that have been employed clinically and experimentally to interrupt wound healing, particularly steroids and the antifibrotic agents 5-fluorouracil and mitomycin ... PJ Lama,RD Fechtner - 《Survey of Ophthalmology》 被引量: 510发表: 2003年
Fracture healing is a complicated process, and numerous studies have demonstrated that vascular function has an essential role in the repair process after fracture. To investigate the effect of metformin on angiogenesis during fracture healing, we first conducted in vitro experiments using human microvasc...
The results demonstrated a statistically significant decrease in the and vascular response of the large versus the small intestine. This differential response may play a role in the mechanism of the relatively high incidence of suture line separations observed after colonic anastomoses. 展开 ...
Firstly, IM acts as a cytotoxic agent inducing necrosis and apoptosis of tumor or viral-infected cells, comparable to fluorouracil (5-FU) or podophyllotoxin. Secondly, IM develops anti-tumor effects by the induction of an inflammatory infiltrate and therefore acts as an ‘immune response modifier...
[67] and can even be used in regenerating the spinal cord [68]. Moreover, UCMSCs may also be a promising therapy for better function and esthetics after cleft repair [69]. However, up until now, only a few studies have shown that UCMSCs could promote intraoral soft tissue regeneration ...
[67] and can even be used in regenerating the spinal cord [68]. Moreover, UCMSCs may also be a promising therapy for better function and esthetics after cleft repair [69]. However, up until now, only a few studies have shown that UCMSCs could promote intraoral soft tissue regeneration ...
and micro dissection was performed using two different sizes of punch biopsy: one punch of 4 mm in diameter was done, around the wound of 3 mm in diameter, to remove the LE zone and one punch of 6 mm in diameter was used to remove the proliferative centre, at D4 and D7 after ...