Ferroptosis is a new iron-dependent form of programmed cell death characterized by iron accumulation and lipid peroxidation. In recent years, ferroptosis has garnered enormous interest in disease treatment rese
Recent progress in ferroptosis inducers for cancer therapy Adv Mater, 31 (51) (2019), Article e1904197 Google Scholar [134] S.J. Dixon, K.M. Lemberg, M.R. Lamprecht, R. Skouta, E.M. Zaitsev, C.E. Gleason, et al. Ferroptosis: an iron-dependent form of nonapoptotic cell death Cel...
Since ferroptosis discovery, it has become a new target for antitumor therapy actively explored by researchers. In this review, we provide an overview of the known mechanisms that regulate the sensitivity of cancer cells to ferroptosis and the research progress of ferroptosis-related drugs (western ...
including but not limited to aggressive types such as breast cancer, liver cancer, stomach cancer, rectal cancer, glioma, and pancreatic cancer [69]. Targeting ferroptosis in the context of lung cancer has the potential to mitigate disease progression and metastasis...
promoting ferroptosis and inhibiting the proliferation of A549 and H1299 cells [108]. These studies open up new avenues for research, specifically in identifying natural compounds from TCM as potential ferroptosis inducers or inhibitors. Another example is erastin, a well-known inducer of ferroptosis;...
Recent progress in targeted delivery vectors based on biomimetic nanoparticles ArticleOpen access07 June 2021 Multicomponent reaction-based combinatorial chemistry for accelerating the discovery of therapeutic protein and nucleic acid delivery materials
ferroptosis inducersiron metabolismnanomedicinetumor microenvironmentFerroptosis is a newly discovered form of regulated cell death that is the nexus between metabolism, redox biology, and human health. Emerging evidence shows the potential of triggering ferroptosis for cancer therapy, particularly for ...
Given the great potential of pyroptosis mechanism and the rapid development of pyroptosis inducers in recent years, it is necessary to summarize the recent progress in this field. In this review, after the pyroptosis mechanisms and characteristics were clarified and the fluorescent probes for pyroptosis...
Ferroptosis inducers enhanced cuproptosis induced by copper ionophores in primary liver cancer J. Exp. Clin. Cancer Res, 42 (2023), p. 142, 10.1186/s13046-023-02720-2 Google Scholar [100] L. Huang, J. Feng, J. Zhu, J. Yang, W. Xiong, X. Lu, S. Chen, S. Yang, Y. Li, Y...
[135]. Thus, we developed a combinatorial treatment strategy involving oxaliplatin and ferroptosis as prodrug-loaded Fe3O4nanoparticles, to improve the ICD effect of oxaliplatin [132]. With advancements in biomedical equipment, micro-invasive PTT and PDT have received increasing attention owing to ...