US5055404 * 1989年8月7日 1991年10月8日 Masamichi Ueda Monoclonal antibody specifically reactive to surface of human prostatic epithelial cellsUS5055404 Aug 7, 1989 Oct 8, 1991 Masamichi Ueda Monoclonal antibody specifically reactive to surface of human prostatic epithelial cells...
ASC, antibody-secreting cell; BCR, B-cell receptor; CDR, complementarity determining region; HBsAg, hepatitis B surface antigen; HepB, hepatitis B; PBMC, peripheral blood mononuclear cell; PC, plasma cellReferences Glanville J, Zhai W, Berka J, Telman D, Huerta G, Mehta GR, et al. Precise...
Antibody-mediated rejection (ABMR) is defined by specific histopathological lesions and evidence of circulating donor-specific antibodies (DSA). Although DSA are not always detectable, monitoring donor-reactive memory B cells (mBC) could identify patients at risk of developing ABMR. Peripheral donor-...
Several lines of evidence suggest a direct relationship between infection, autoimmunity and cancer. Hepatitis B and C viruses are involved in an autoimmune condition that precedes the development of hepatocellular carcinoma [209]. Data also demonstrate a higher prevalence of B-cell non-Hodgkin's lymph...
Monocytic myeloid-derived suppressor cells (M-MDSCs) were increased during LP-BM5 retroviral infection, and were capable of suppressing not only T-cell, but also B-cell responses. In addition to previously demonstrating iNOS- and VISTA-dependent M-MDSC mechanisms, in this paper, we detail how...
Drug delivery of an antibody-enzyme conjugate of an antibody (monoclonal antibody L49) reactive with an antigen on the surface of tumor cells conjugated to an enzyme ( beta-lactamase) that converts a nitrogen mustard-type prodrug into the more cytotoxic parent drug...
monoclonal antibody cross-reactive to DENV and JEV recognizes the 106th amino acid residue of the E protein of JEV (E-106). The JE DNA vaccine with a mutation at E-106 (E-106 vaccine) induced comparable neutralizing antibody titers against JEV to those induced by the wild-type JE DNA ...
Exposure to ubiquitous endocrine-disrupting chemicals (EDCs) is a major public health concern. We analyzed the physiological impact of the EDC, di-2-ethylhexyl phthalate (DEHP), and found that its metabolite, mono-2-ethylhexyl phthalate (MEHP), had signi
Anti-citrullinated protein antibody PBMC: Peripheral blood mononuclear cells FGB: Fibrinogen beta chain LN: Lymph node LURA: Lung investigation in early RA patients DAS: Disease activity score RF: Rheumatoid factor HA: Hemagglutinin MP: Matrix protein PHA: Phytohemagglutinin IL-2: Inter...
Cohort studies of antibody and B cell cross-reactivity Several studies have explored the potential effect of cross-reactive antibodies and T cells on COVID-19 severity. Although cross-reactive antibodies against SARS-CoV-2 spike protein domains can be detected in pre-pandemic samples and may neutra...