RB-E2F1doi:10.4161/auto.6.8.13695HongBrainJiangBrainVanesaBrainMartinBrainMartaBrainAlonsoBrainCandelariaBrainGomez-ManzanoBrainJuanBrainFueyo-MargaretoBrainInformaworldAutophagyRB-E2F1[J] . Hong Jiang,Vanesa Martin,Marta Alonso,Candelaria Gomez-Manzano,Juan Fueyo-Margareto.Autophagy . 2010 (8)...
方法: 应用RT-PCR法对48例新疆哈萨克族食管鳞癌组织及其配对的癌旁正常组织进行Rb和E2F1表达检测, 分析Rb/E2F1通路与新疆哈萨克族食管鳞癌发生发展之间的关系. 结果: 新疆哈萨克族食管鳞癌组织中Rb的阳性表达高于癌旁正常组织(64.6%, 43.8%)差异有统计学意义(P<0.05); 转录因子E2F1的阳性表达率与癌旁正常组织阳性...
that FGF9‐induced Rb phosphorylation led to the dissociation of Rb‐E2F1 complexes and thereby enhanced the transactivations of E2F1 target genes, Cyclin D1, Cyclin E1 and Cyclin A1. Silencing of FGF receptor 2 (FGFR2) us...
Rb, indicating that loss ofCdkn1aenables progression of cell cycle. Moreover, the transcription factor E2F1 induces EZH2 during the GC reaction.E2f1−/−mice manifest impaired GC responses, which is rescued by restoring EZH2 expression, thus defining a positive feedback loop in which EZH2 ...
A functional variant at the miRNA binding site in E2F1 gene is associated with risk and tumor HPV16 status of oropharynx squamous cell carcinoma Human papillomavirus (HPV) activates E2F1-driven transcription via the E7-RB1-E2F pathway. Genetic polymorphisms in the 3鈥 untranslated region (UTR) tar...
Interaction among Rb/p16, Rb/E2F1 and HDAC1 Proteins in Gallbladder Carcinoma Lining XUSurgery华中科技大学学报:医学英德文版Xin Wang,Kai Huang,Lining Xu.Interaction among Rb/p16, Rb/E2F1 and HDAC1 proteins in gallbladder carcinoma[J... X Wang,K Huang,XU Lining - 《华中科技大学学报:医学英德文...
MCPIP1 downregulates cyclin D1-Rb-E2F1 axis via CTF5 A previous study reported that NFIC could directly repress cyclin D1 transcription through binding to the promoter of cyclin D1 in breast cancer42. To explore whether CTF5 inhibits cyclin D1 expression, we quantified the expression level of...
E2f1, but Not E2f2 or E2f3, Loss Rescues Ectopic Division and Cell Death in the Rb KO RetinaDanian, Chen
2. shRNA HDAC1重组干扰质粒干扰降低PC-3M细胞中HDAC1mRNA的表达水平,对RB1和E2F1基因mRNA的表达无显著影响. 3. shRNA HDAC1重组干扰质粒抑制PC-3M细胞中HDAC1mRNA的表达,能够阻抑PC-3M细胞周期,进而诱导细胞凋亡. 展开 关键词: HDAC1shRNA RB1 E2F1 前列腺癌 细胞周期 ...