Ras-related small GTP-binding proteinABA receptorStomatal movementDroughtDrought represents a leading constraint over crop productivity worldwide. The plant response to this stress is centered on the behavior of
The role of the Ras-related GTP-binding protein, Rab1B, in intracellular trafficking of β-amyloid precursor protein (βAPP) was studied in cultured 293 cells. βAPP is processed via one of two alternative routes. In the major secretory pathway,βAPP is cleaved by α-secretase within the ...
RelatedGTP-BindingProtein(Rheb)inUVSusceptibilityKazukoKita,*,1Yu-PingWu,*ShigeruSugaya,*TetsuhiroMoriya,*JunNomura,*ShunjiTakahashi,*HideoYam..
Twitter Google Share on Facebook RAB12 (redirected fromras-related protein Rab-12) RAB12 A gene on chromosome 18p11.22 that encodes a member of the Rab subfamily of Ras-related small GTPases, which is involved in vesicle trafficking.
RAF protein kinases are major RAS effectors that function by phosphorylating MEK. Although all three RAF isoforms share a conserved RAS binding domain and bind to GTP-loaded RAS, only ARAF uniquely enhances RAS activity. Here we uncovered the molecular basis of ARAF in regulating RAS activation. ...
* Correspondence: laizx01@163.com; Tel.: +86-591-8378-9484 Academic Editor: Jianhua Zhu Received: 19 March 2016; Accepted: 23 May 2016; Published: 3 June 2016 Abstract: Ras-related guanosine triphosphate (GTP)-binding nuclear protein (Ran) GTPases function as molecular switches and ...
英文别名 Aplysia ras related homolog 12 | ARH12 | ARHA | H 12 | H12 | Oncogene RHO H12 | Ras homolog family member A | Ras homolog gene family member A | Rho A | Rho cDNA clone 12 | RHO H12 | RHO12 | RHOA | RHOA_HUMAN | RHOH12 | Small GTP binding protein Rho A | T ...
[31]. The GRDs of IQGAPs show high homology with the RasGAP domains of RasGAP proteins, which deactivate GTPases by simulating GTP hydrolysis, but GRDs are inactivated by mutations of crucial residues [31,32,33,34,35]. Instead, GRDs together with RGCt domains mediate the binding of ...
R-ras like TC21, is evolutionarily distant to H-ras, K-, or N-ras. But all of these proteins share a highly conserved N-terminal catalytic domain with effector binding sequences (amino acid sequence 32-40 in H-ras) (Valencia et al, 1991). Of all the small GTP-binding proteins with...
The rgp1 gene, originally Isolated from rice seedlings, encodes a small GTP-binding protein which is related to the product of the human proto-oncogene, ras-p21. To determine the physiological role of the rgp1 protein, rgp1-p25, the coding region of rgp1 was introduced into tobacco ...