Ly-GDI, a GDP-dissociation inhibitor of the RhoA GTP-binding protein, is expressed preferentially in lymphocytes The Ras-related small GTP-binding proteins are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and... P Scherle,BLM Staudt - 《Proc...
The regulatory function of the Ras-like GTPases in diverse cellular processes, such as growth, cell movement, and protein trafficking, is critically depend... MC Seabra - 《Cellular Signalling》 被引量: 441发表: 1998年 Measurement of GTP-bound Ras-like GTPases by activation-specific probes....
英文名字 Rac1 (Ras-related C3 Botulinum Toxin Substrate 1, Rho Family, Small GTP Binding Protein Rac1, Cell Migration-inducing gEne 5 Protein, MGC111543, MIG5, p21-Rac1, Ras-like Protein TC25)供应商 MyBioSource产品货号 MBS631427产品报价 ￥询价/0.05mg ￥询价/5x0.05mg ￥询价/其它规格产品...
to RasGEFs 36 , and later as a protein which inter- � acts with the GTP-bound form of Ras and several . other Ras-like GTPases, see below in yeast two w x hybrid screens 37,38 . Two distant relatives with w x similar structural and binding properties, Rgl 39 and w x Rlf 40...
Thus, Rad is a GTP-binding protein and a GTPase which has some structure/function similarities to Ras, but displays unique features. Rad may also be phosphorylated on serine/threonine residues by PKA and other kinases, as well as regulated by its own GAP which is present in many tissues ...
Small guanosine 5′-triphosphatases (GTPases) of the Ras superfamily switch between a guanosine 5′-diphosphate (GDP)-bound and a guanosine 5′-triphosphate (GTP)-bound conformation. This cycle is regulated by guanine nucleotide exchange factors that release the bound nucleotide. Since the concentr...
Ras guanine nucleotide-releasing protein (RasGRP) is one type of GEF (GTP/GDP exchange factor) responsible for the activation of Ras and/or Rap14,15. Each protein contains a Ras exchange motif to interact with Ras and/or Rap, CDC25, EF hands for Ca2 þ binding and C1 domain for ...
Small GTP-binding proteins of the Rab and Arf (ADP-ribosylation factor) families play a central role in the membrane trafficking pathways of eukaryotic cells. The prototypical members of the Arf family are Arf1-Arf6 and Sar1, which have ... K Kurokawa,T Nakamura,K Aoki,... - 《Portland...
The regulatory function of the Ras-like GTPases in diverse cellular processes, such as growth, cell movement, and protein trafficking, is critically depend... MC Seabra - 《Cellular Signalling》 被引量: 441发表: 1998年 Measurement of GTP-bound Ras-like GTPases by activation-specific probes....
VPS21 encodes a rab5-like GTP binding protein that is required for the sorting of yeast vacuolar proteins. The gene affected in one such mutant, vps21, has been cloned and found to encode a member of the ras-like GTP binding protein family. Sequence ... Horazdovsky, B.F.,Busch, G....