This was the case, for example, in the Cardiac Arrhythmia Suppression Trial (CAST), which was halted early due to increased fatality in the active treatment arm.18 In randomized clinical trials, persons from a well-defined study population are assigned to treated or untreated groups at rando...
Implementing a randomized clinical trial on a pediatric psychiatric inpatient unit at a children's hospital: the case of clonidine for post‐traumatic stress. General Hospital Psychiatry. Nov‐Dec 2002;24(6):422‐429....
clinicians share experiences andreal worlddata regarding the effectiveness of talk therapy. For example, ICCE associateDan Buccinoshared outcomes from a 7 year project aimed at “promoting recovery and accountability.” Using theOutcome and Session Ratings Scales, Dan documented...
single-center, open-label trial tested the impact of a mobile health (mHealth) service tool optimized for ASCVD patient care. Patients with clinical ASCVD were enrolled and randomly assigned to the intervention or control group. Participants in the intervention ...
Cancer Trial (5-FU & Radiation) Gastric Carcinoma According to treatment received 5 year survival Received % Survival Treatment 20% Refused Treatment 30% NS Control 4% Example: Coronary Drug Project 5-Year Mortality Clofibrate Placebo N % Deaths N % Deaths ...
Database, China Dissertation Database, and online clinical trial registry websites for published and unpublished randomized clinical trials (RCTs) of CPMs for the common cold till 31 March 2013. Revman 5.2 software was used for data analysis with effect estimate presented as relative risk (RR) ...
Clinical trial design has dramatically evolved with the advent of precision medicine. As a result, expedited drug-approval decisions have been made on the basis of evidence obtained in uncontrolled clinical trials. Herein, Saad et al. discuss the need to
This clinical trial assesses whether landiolol for patients with tachycardia and established septic shock requiring prolonged vasopressor support reduces
This randomized clinical trial examines the sustained effects of a preschool home visiting program on child and family competencies and on child need for
The resistance training consisted of three sets in the main muscle groups, for example, chest press, leg press, back row, and leg extension. The 8–12 repetitions aimed at a resistance consistent with 0–3 repetitions in reserve46. All heart-rate profiles were recorded during the exercise ...