A number of innovative strategies have been explored in order to minimize the exposure of subjects included in clinical trials to either placebo or ineffective novel drug candidates. These strategies are particularly important in the area of psychopharmacology where the morbidity associated with a ...
Randomization in clinical trials is a tool to minimize differences between the groups to be studied at the start of the trial, typically the treatment group and the comparator. Thus, every group should have a similar distribution of relevant predefined demographic data and disease parameters. Moreov...
Randomization in Clinical Trials 作者: William F·Rosenberger 出版社: John Wiley & Sons Inc出版年: 2002-7页数: 288定价: 1158.00 元装帧: HRDISBN: 9780471236269豆瓣评分 评价人数不足 评价: 写笔记 写书评 加入购书单 分享到 推荐 内容简介 ··· A unique overview that melds the concepts of condi...
Presents a firm mathematical basis for the use of response-adaptive randomization procedures in practiceThe Theory of Response-Adaptive Randomization in Clinical Trials is the result of the authors' ten-year collaboration as well as their collaborations with other researchers in investigating the ...
Sealed Envelope provide high quality and easy to use online software applications for randomising patients into clinical trials and recording their case report form data (EDC and ePRO)
process when evaluating different randomization design options at the study planning stage. The “Conclusions” section summarizes the key findings and important considerations on restricted randomization procedures, and it also highlights some extensions and further topics on randomization in clinical trials....
The “Methods” section provides some general background on the methodology of randomization in clinical trials, describes existing restricted randomization procedures, and discusses some important criteria for comparison of these procedures in practice. In the “Results” section, we present our findings...
Clinical Trials:Clinical trials involve the research done to test the treatments available to the people. It includes participating people called volunteers that answer questions related to the medical treatment and are evaluated to screen the results....
Lachin, «Randomization in Clinical Trials: Theory and Practice» Wiley-Interscience | ISBN 0471236268 | 2002 Year | DjVu | 2,63 Mb | 288 Pages "…excellent for learning on how to use randomization ideas…" (Journal of Statistical Computation & Simulation, May 2004) "This book ...
Response-adaptive randomization in clinical trials uses accumulated patient response data to adjust the allocation probability for the next patient, so that a particular objective, for example, more...doi:10.1007/978-1-4939-1100-4_10Lanju Zhang...