There are several types of clinical trials. A single-arm trial has no comparison group. A randomized controlled trial (RCT) has two groups of patients, each of which may receive either the test treatment or a harmless placebo. Depending on the trial design, the allocation of the drug vs. ...
doi:10.1016/0741-5214(91)90317-NHobsonSection of Vascular Surgery, University of Medicine and Dentistry of New Jersey, Newark.Robert W.Section of Vascular Surgery, University of Medicine and Dentistry of New Jersey, Newark.Journal of Vascular Surgery...
STUDY SELECTION: Discriminatory accuracy studies of breast cancer risk assessment methods; randomized clinical trials of tamoxifen, raloxifene, and aromatase inhibitors for primary breast cancer prevention; studies of medication adverse effects. DATA EXTRACTION AND SYNTHESIS: Investigators abstracted data on me...
Evidence-based medicine, systematic reviews, and guidelines in interventional pain management: Part 2: Randomized controlled trials. Evidence-based medicine (EBM) is a shift in medical paradigms and about solving clinical problems, acknowledging that intuition, unsystematic clinical expe......
Consent and randomized clinical trials: are there moral or design problems? The purpose of this paper is to examine whether randomized clinical trial (RCT) methods are necessarily morally problematic. If they are intrinsically prob... Kopelman - 《Journal of Medicine & Philosophy》 被引量: 14发表...
A systematic review of randomized controlled trials was undertaken. Only trials that identified exercise to be effective in treating patellofemoral pain were included. Appropriate databases and reference lists were searched using established keywords. Data relating to common exercise parameters such as the ...
aUnlike many other clinical trials, Phase IV studies are not typically randomized or placebo controlled. Instead, these trials are "open label" all subjects are given the newly approved product, and they and their caregivers know what that product is. Medical Affairs teams often conduct these ...
: What can we gain? Parallel randomized and nonrandomized clinical trials: What can we gain?Parallel randomized and nonrandomized clinical trials: What can we gain?doi:10.1016/0197-2456(91)90203-XSueM.MarcusSDOSControlled Clinical Trials
What Are the Clinical Criteria Justifying Spinal Manipulative Therapy for Neck Pain? A Systematic Review of Randomized Controlled Trials Smith J, Bolton PS: What are the clinical criteria justifying spinal manipulative therapy for neck pain? A systematic review of randomized controlled trials... S ...
One example of an interventional study is a randomized control trial (RCT). During a randomized control trial, human subjects are chosen at random to receive an intervention. Generally, participants are arbitrarily placed into one of two groups: the experimental group receiving the intervention that...