Unfortunately, damaging effects to normal lung inside the radiation field are unavoidable, leading to the clinical syndromes "radiation pneumonitis" and "radiation fibrosis." Onset of disease occurs 6 weeks to 6 months after radiation and includes symptoms of dyspnea, cough, chest pain, and fever....
Rabbit model of radiation-induced lung injury Objective To explore the feasibility of establishing an animal model of chronic radiation-induced lung injury. Methods Twenty-eight New Zealand white rabbi... Zhen-Zong Du and Hua Ren and Jian-Fei Song and Li-Fei Zhang and Feng Lin and Hai-Yong ...
It has also been used as a palliative remedy to alleviate symptoms in malignant and non-malignant disorders [2]. However, radiation-induced lung injury (RILI) is a severe complication of thoracic RT and embraces radiation pneumonitis (RP) and radiation fibrosis (RF) [3]. With the advent of...
Radiation-induced lung injury after concurrent neoadjuvant chemoradiotherapy for locally advanced breast cancer. Acta Oncol. 2014; 53 :697–701. doi: 10.3109/0284186X.2013.871387. [ Cross Ref ]Chow TL, Louie AV, Palma DA, et al. Radiation- induced lung injury after concurrent neoadjuvant ...
Radiation-induced lung injury (RILI) is a complication of thoracic RT, which is commonly used in the treatment of lung cancer, mediastinal lymphoma, and breast cancer. RILI may manifest acutely as radiation pneumonitis or later as radiation-induced pulmonary fibrosis. [27] Radiation pneumonitis [27...
This study aimed to find a better dosimetric parameter in predicting of radiation-induced lung toxicity (RILT) in patients with non-small cell lung cancer (NSCLC) individually: ventilation(V), perfusion (Q) or computerized tomography (CT) based. V/Q sing
Multiple competing normal tissue complication probability (NTCP) models have been proposed for predicting symptomatic radiation-induced lung injury in human. In this paper we tested the efficacy of four common NTCP models applied quantitatively to sub-cl
A retrospective analysis is performed to determine if pre-treatment [18 F]-2-fluoro-2-deoxyglucose positron emission tomography/computed tomography (FDG PET/CT) image derived parameters can predict radiation pneumonitis (RP) clinical symptoms in lung cancer patients. Methods and Materials We retrosp...
General Principles Radiation-induced liver injury is rare. It may occur after radiotherapy with at least 30 Gy, such as may be seen in patients with lung cancer, metastatic ovarian carcinoma, or malignant abdominal lymphomas. Even after localized liver radiation with 1,500 Rad, liver weight is ...
injury by down-regulating GPX4 expression [62]. Based on these findings, gut bacteria may thus influence radiation-induced ferroptosis via several mechanisms. RIII remains a debilitating side effect of radiation therapy, leaving a considerable number of patients with acute or chronic symptoms. Further...