RADIATION-INDUCED FIBROSIS TREATMENTDisclosed herein is a pharmaceutical composition for use in the treatment or prevention of radiation-induced fibrosis, wherein the composition comprises an extract of Trigonella foenum-graecum and optionally pharmaceutically acceptable additives.OLSEN, JENS STEEN...
Fibrosis is a common sequela of both cancer treatment by radiotherapy and accidental irradiation and has been described in many tissues including skin, lung, heart and liver. The underlying mechanisms of the radiation-induced fibrosis still remain to be resolved. In the present review we tried to...
The mice were observed for 16weeks, and excessive deposition of type I collagen was suppressed by sLRP6E1E2-expressing adenovirus treatment. These results demonstrate that the modulation of the Wnt/尾-catenin pathway has the potential to decrease the severity of radiation-induced dermal fibrosis....
fibrosis may significantly alter tissue form and function and profoundly impact patient quality of life43. RIF is a progressive disease that worsens over months and years following radiation treatment. As such, preventing
Combination treatment with topicals, systemics, or phototherapy is more likely to induce a clinical response (Cheah et al., 2008Friedman et al., 2018, Fruchter et al., 2017, Mittal et al., 2019, Newland and Marshman, 2012 Spalek et al., 2015). Radiation-induced fibrosis Radiation-induced...
LXA4-FPR2 signaling regulates radiation-induced pulmonary fibrosis via crosstalk with TGF-β/Smad signaling Radiation therapy is an important modality in the treatment of lung cancer, but it can lead to radiation pneumonitis, and eventually radiation fibrosis. To... H Kim,SH Park,YH Song,... ...
Cytokines e.g transforming growth factor β (TGF-β) might be involved in the induction of fibrosis. Treatment use emollients. Superoxide dismutase was used as an ointment for radio-fibrosis therapy and obtains a reduction of the fibrosis. In late phases plastic surgery or sometimes cryo-surgery...
TST/NMES is a plausible prophylaxis and/or treatment for RT-induced muscle fibrosis and dysphagia. J. Surg. Oncol. 2016 Wiley Periodicals, Inc. 2016 Wiley Periodicals, Inc.doi:10.1002/jso.24265Peng, GraceMasood, KamilGantz, OliverSinha, Uttam...
Unfortunately, damaging effects to normal lung inside the radiation field are unavoidable, leading to the clinical syndromes "radiation pneumonitis" and "radiation fibrosis." Onset of disease occurs 6 weeks to 6 months after radiation and includes symptoms of dyspnea, cough, chest pain, and fever....
Moreover, this ECV increase was linear with the radiation dose per LV segment, indicating radiation-induced myocardial fibrosis.doi:10.1016/j.ijrobp.2021.02.007Crystal de GrootJannet C. BeukemaJohannes A. LangendijkHans Paul van der LaanNiek H.J. Prakken...