Radiation-induced brain injury (RIBI) is one of the most common and fatal complications of cranial radiation therapy (CRT); however, no effective intervention is available currently. Metformin has been reported to have anti-RIBI activity as a first-line anti-diabetic drug. How...
The adverse effects caused by RIBI have not yet been effectively resolved.Radiation-induced brain injury causes hippocampal neuronal apoptosis.BMSCS activa... K Xu,Z Liu,S Pan,... - 《Brain Research》 被引量: 0发表: 2024年 Deformation-based morphometry: a sensitive imaging approach to detect...
Objective To determine the extent to which Lycium barbarum polysaccharide (LBP) improves 60Co γ-ray radiation-induced brain injury (RIBI) by regulating the gut microbiota. Methods The RIBI model of mice was established with the appropriate dose of 60Co γ-ray to identify the changes in the bo...
Shenqi fuzheng injection attenuates irradiation-induced brain injury in mice via inhibition of the NF-κB signaling pathway and microglial activation. Radiation-induced brain injury (RIBI) is the most common and severe adverse effect induced by cranial radiation therapy (CRT). In the present study, ...
have helped to reduce the amount of radiation-induced injury in surrounding normal tissues. Nevertheless, radiation-induced brain injury (RIBI) remains a common and severe side-effect of CRT. Survivors of irradiated childhood brain tumors who develop late-delayed cognitive deficits due to RIBI may ...
Background: Radiation-induced brain injury (RIBI) is a debilitating sequela after cranial radiotherapy. Research on the topic of RIBI has gradually entered the public eye, with more innovations and applications of evidence-based research and biological mechanism research in the field of that. This ...
Radiation-induced brain injuryKukoamine AOxidative stressApoptosisRadiation-induced brain injury (RIBI) is a prominent side effect of radiotherapy for cranial tumors. Kukoamine A (KuA) has the ability of anti-oxidative stress and anti-apoptosis in vitro. The aim of this study was to investigate ...
Radiation-induced brain injury (RIBI) shows obvious impairments of the blood鈥揵rain barrier (BBB). In the neuroinflammatory processes after acute brain injury, a large amount of complement proteins and infiltrated immune cells are circulated in the CSF to resist brain damage and ...
Objective:To determine the extent to which Lycium barbarum polysaccharide(LBP)improves 60Co g-ray radiation-induced brain injury(RIBI)by regulating the gut microbiota.Methods:The RIBI model of mice was established with the appropriate dose of 60Co g-ray to identify the changes in the body weight...
Radiotherapy for head and neck tumors can lead to a severe complication known as radiation-induced brain injury (RIBI). However, the underlying mechanism of RIBI development remains unclear, and limited prevention and treatment options are available. Neuroactive steroids have shown potential in treating...