Rac1 gtpase, a multifunctional player in the regulation of genotoxic stress response. Cell Cycle 12 (16), 2521-2522.Fritz, G., Kaina, B., 2013. Rac1 GTPase, a multifunctional player in the regulation of genotoxic stress response. Cell Cycle. 12, 2521-2522....
Rac1 GTPase is a member of the Rho family of small GTPases, which play critical roles in the regulation of various cellular processes that include reorganization of the actin cytoskeleton, cell-cycle progression, intercellular adhesion, and gene expression [reviewed in [1]]. Rho family proteins...
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. These experiments showed that the GTPase is further recruited to the PVM during intraerythrocytic growth and suggest a possible role of the protein also in this phase of the life cycle. We could not determine precisely Rac1 localization in the schizont stage, because the signal is widespread ...
Although little is known about the roles and regulation of PP5 in breast epithelial cells, this phosphatase has been reported to be elevated in breast cancer and is also implicated in the promotion of cell proliferation, primarily through inhibition of pathways initiating cell cycle arrest and ...
Racl蛋白活化与内皮细胞通透性和细胞骨架改变的相关研究硕士研究生:孟子敏指导教师:**玲教授专业名称:内科学摘要研究背景及目的在多器官功能衰竭(multipleorganfailure,MOF)和全身性炎症反应综合征(systemicinflammatoryresponsesyndrome,SIRS)发生中,来自循环斑液病原体和/或其毒素以及由此而刺激产生的细胞因子如肿瘤坏死因子...
Cervical cancer (CC) is the most frequently diagnosed genital tract cancer in females worldwide. Rac GTPase-activating protein 1 (RacGAP1) is one of the specific GTPase-activating proteins. As a novel tumor protooncogene, overexpression of RacGAP1 was re
rac 1 / cdc42 phospho (ps71) (cdc42) antibody rabmab® cat.#: 2467-1 rabbit monoclonal antibody clone id:ep221y swiss prot:p60953 mol weight:23kda size:100ul price: view datasheet description rac1 and cell division cycle 42 (cdc42) are guanosine triphosphatases (gtpases). rac1 ...
PJ-539 Novel Role of Rac1 in the Transcriptional Up-regulation of p27^ and Cell Cycle Arrest in Vascular Endothelial Cells(Molecular biology, vascular(02)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society) 喜欢 0 阅读量: 19 作者: Hirano,...
the proliferation cycle is longer, inhibition of Rac1 does not significantly affect its proliferation but can significantly reduce the post-radiation ROS production and apoptosis, which ultimately shows a protective effect. However, Rac1 is over-expressed in tumor cells. Many studies have shown that...