网络释义 1. 鸟苷酸酶循环 【gtpase】什么意思_英语gtpase在线翻译_有道词典 ... Ran GTPase 接蛋白GTPase cycle鸟苷酸酶循环Rho GTPase GTP … dict.youdao.com|基于 1 个网页
Deactivation at the transducin level is coupled to the hydrolysis of transducin-bound GTP by the intrinsic GTPase activity ( Fung et al. 1981). Once T-GTP is removed, the P 纬 subunit recombines with the catalytic P 伪尾 subunits of PDE and turns off the hydrolysis of cGMP ( Hurley and...
We demonstrate that the switching betweenGTP and GDP binding states, which is governed by guanine nucleotideexchange factors (GEFs), GTPase-activating proteins (GAPs), GDI, andGDI displacement factor (GDF), is a major determinant of Rab1'sability to effectively cycle between cellular compartments ...
The small GTPase Ran has been found to play pivotal roles in several aspects of cell function. We have investigated the role of the Ran GTPase cycle in spindle formation and nuclear envelope assembly in dividing Caenorhabditis elegans embryos in real time. We found that Ran and its cofactors Ra...
GTPase cycle. We demonstrate that the NAD+-dependent deacylase SIRT2 removes the myristoyl group, and our evidence suggests that NMT prefers the GTP-bound while SIRT2 prefers the GDP-bound ARF6. This allows the lysine myrisotylation-demyristoylation cycle to couple to and promote the GTPase ...
RCC1, the chromatin-bound guanine-nucleotide exchange factor (GEF) for the small nuclear GTPase, Ran, is required for coordinating the onset of mitosis with S-phase completion in mammalian cells. Other defects in the Ran-GTPase network also result in disruption of cell-cycle processes such as ...
Cell cycle arrest in Era GTPase mutants: a potential growth rate-regulated checkpoint in Escherichia coli. Mol. Microbiol. 27: 739-750.Britton, R.A., Powell, B.S., Dasgupta, S., Sun, Q., Margolin, W., Lupski, J.R., and Court, D.L. (1998) Cell cycle arrest in Era GTPase ...
The small GTPase Ran is a Ras-related GTPase that acts in diverse cellular processes. One of the functions of Ran is to regulate the nucleocytoplasmic transport of molecules through the nuclear pore complex [5], [6], [7], [8]. In addition, Ran is involved in cell cycle progression throu...
Ran GTPase: a master regulator of nuclear structure and function during the eukaryotic cell division cycle? 来自 万方 喜欢 0 阅读量: 97 作者:Paul R Clarke a,Chuanmao Zhang a b 摘要: Ran is an abundant GTPase that is highly conserved in eukaryotic cells and has been implicated in many ...
Conversely, Mfn1-K88T, a GTPase mutant, increases FRAP recovery compared to Mfn1 and Mfn1-rasG12V (Mfn1-K88T>Mfn1rasG12V>Mfn1). Thus the submitochondrial localization and mobility on the mitochondrial membrane change as the two mitofusins transit through their GTPase cycles.doi:10.1096/fasebj....