hygroscopic; unpleasant odor; burning taste; slightly alkaline in reaction; soluble in water, alcohol, ether, benzene, and fatty oils; specific gravity, 0.978; autoignition temperature, 482 °C. Pyridine, a tertiary amine, is a somewhat stronger base than aniline and readily forms quaternary ammoni...
Another example of a pyridine containing medication is loratadine, more commonly known by its brand name of Claritin. Loratadine helps in the treatment of allergies.3.3 PesticidesThe main use of pyridine is as a precursor to the herbicides paraquat and diquat. The first synthesis step of ...
156,157 The product is a rare case of unsupported Au(i)–Au(iii) donor/acceptor bonding, which is even less readily explained by conventional concepts than the more abundant aurophilic bonding between two or more gold(i) centers. Similar observations have been made in reactions summarized in ...
A Pyrrolopyridine is a colorless and almost odorless compound with higher melting points and greater stability in acidic or basic solutions compared to indole. It is also a considerably stronger base than indole. AI generated definition based on: Comprehensive Heterocyclic Chemistry II, 1996 ...
Lookchem Provide Cas No.538-49-8 Basic information: Properties,Safety Data,Sds and Other Datebase. We also Provide Trading Suppliers & Manufacture for 538-49-8 2-(2-Phenethenyl)pyridine.
Peptide coupling reagents, more than a letter soup. Chem. Rev. 111, 6557–6602 (2011). 24. Mosher, H. S. & Look, M. Heterocyclic basic compounds XVI. 4-Chloropicolinic acid and some of its derivatives. J. Org. Chem. 20, 283–286 (1955). 25. Bankston, D. et al. A scaleable...
8 Alkylaqua complexes of cobalt(III) are more soluble in alcohols or water than their pyridine derivatives, and thus are well suited for introducing any ligand which is more prone to bind to coordinated cobalt(III) than water (the latter property is in general well correlated with the ...
Accordingly, there is a need for new compounds that inhibit Pim kinases. The present application describes new inhibitors of Pim kinases that are useful for treating diseases associated with the expression or activity of one or more Pim kinases, e.g., cancer and other diseases. SUMMARY The pres...
more heteroatoms selected from N, O and S, wherein the ring system is optionally substituted by one or more Z substituents; or R4 and R5 and R6 together with the carbon atoms to which they are bound form a 5 to 8 membered heterocyclic ring system containing one or more heteroatoms ...
Suitable values for R4include hydrogen, methyl, ethyl, n- and iso-propyl and benzyl. More suitably R4is hydrogen or 2-methyl. Favourably R4is hydrogen. It will be appreciated that when R4is hydrogen the compounds of formula (I) exist as tautomers, i.e. the R4hydrogen atom is labile. ...